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口腔链球菌形成的属内和属间相互作用:在口腔疾病发病机制中的关键作用。

Intrageneric and Intergeneric Interactions Developed by Oral Streptococci: Pivotal Role in the Pathogenesis of Oral Diseases.

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China.

出版信息

Curr Issues Mol Biol. 2019;32:377-434. doi: 10.21775/cimb.032.377. Epub 2019 Jun 5.

DOI:10.21775/cimb.032.377
PMID:31166176
Abstract

Oral streptococci are among the most abundant genera present in the oral cavity. They are usually the first colonizers of oral surfaces and they develop extensive microbial interactions, playing a fundamental role in the pathogenesis of oral diseases such as dental caries and periodontitis. In addition to physical adherence, streptococcal cells also exchange messages with cells from another spp. and other microorganisms in the form of metabolites and signaling molecules. In this review, we focused on these intrageneric and intergeneric interactions, and their association with oral diseases.

摘要

口腔链球菌属是口腔中最丰富的属之一。它们通常是口腔表面的最初定植者,并与其他微生物发生广泛的相互作用,在龋齿和牙周炎等口腔疾病的发病机制中发挥着重要作用。除了物理附着外,链球菌细胞还以代谢物和信号分子的形式与其他 spp. 和其他微生物的细胞进行信息交流。在这篇综述中,我们重点讨论了这些属内和属间相互作用及其与口腔疾病的关系。

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