Olmo Roenick P, Martins Nelson Eduardo, Aguiar Eric Roberto G R, Marques João T, Imler Jean-Luc
Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, Strasbourg, France.
Department of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
An Acad Bras Cienc. 2019;91 Suppl 3:e20190122. doi: 10.1590/0001-3765201920190122. Epub 2019 Jun 3.
Insects are the most diverse group of animals. They can be infected by an extraordinary diversity of viruses. Among them, arthropod-borne viruses (arboviruses) can be transmitted to humans. High-throughput sequencing of small RNAs from insects provides insight into their virome, which may help understand the dynamics of vector borne infectious diseases. Furthermore, investigating the mechanisms that restrict viral infections in insects points to genetic innovations that may inspire novel antiviral strategies.
昆虫是动物中种类最为多样的群体。它们可被种类异常繁多的病毒感染。其中，节肢动物传播病毒（虫媒病毒）能够传播给人类。对昆虫的小RNA进行高通量测序有助于深入了解其病毒组，这可能有助于理解媒介传播传染病的动态变化。此外，研究限制昆虫体内病毒感染的机制能揭示可能启发新型抗病毒策略的基因创新。
