Bouthier J D, Simon A C, Levenson J
Unité INSERM Z8, Hôpital Broussais, Paris, France.
Arch Mal Coeur Vaiss. 1987 Jun;80(6):771-5.
The brachial artery diameter and blood flow rate were measured by pulsed Doppler velocimetry in 9 healthy subjects and 24 patients of the same age group with borderline hypertension. To evaluate the results, the patients were divided into two groups according to their cardiac output: high cardiac output group (i.e. patients whose cardiac output was superior to the mean +/- 2 S.D. value in the control population), and normal cardiac output group (i.e. cardiac output lower than that value). Patients in both groups were of the same age and had the same level of blood pressure. The brachial artery diameter and blood flow rate values were the same in the normal cardiac output group and in the control population. However, these values were significantly higher in patients with high cardiac output than in controls (P less than 0.05 and P less than 0.001) and in patients with normal cardiac output (P less than 0.01). These results suggest that the haemodynamic profile in the brachial artery is not the same in all patients with borderline hypertension: there was a tendency to vasoconstriction in patients with normal cardiac output, whereas the brachial artery was clearly dilated in patients with high cardiac output.
采用脉冲多普勒测速法对9名健康受试者和24名同年龄组临界高血压患者的肱动脉直径和血流速度进行了测量。为评估结果,根据心输出量将患者分为两组:高心输出量组(即心输出量高于对照组人群均值±2个标准差的患者)和正常心输出量组(即心输出量低于该值的患者)。两组患者年龄相同,血压水平相同。正常心输出量组的肱动脉直径和血流速度值与对照组人群相同。然而,高心输出量患者的这些值显著高于对照组(P<0.05和P<0.001)以及正常心输出量患者(P<0.01)。这些结果表明,并非所有临界高血压患者肱动脉的血流动力学特征都相同:正常心输出量患者有血管收缩的倾向,而高心输出量患者的肱动脉明显扩张。