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症状性颈内动脉近段闭塞患者颈动脉内膜切除术与支架置入术的比较。

Comparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-Occlusion.

机构信息

From the Departments of Neurology, Neurosurgery, and Radiology (J.K., S.M., R.P.T.), University of Minnesota, Minneapolis, Minnesota

From the Departments of Neurology, Neurosurgery, and Radiology (J.K., S.M., R.P.T.), University of Minnesota, Minneapolis, Minnesota.

出版信息

AJNR Am J Neuroradiol. 2019 Jul;40(7):1207-1212. doi: 10.3174/ajnr.A6085. Epub 2019 Jun 6.

Abstract

BACKGROUND AND PURPOSE

Carotid near-occlusion is defined as severe stenosis of the internal carotid artery with partial or full collapse of the distal vessel wall. The major studies evaluating carotid revascularization excluded patients with carotid near-occlusion. Given the paucity of data in the literature, we attempted to evaluate the safety of carotid endarterectomy and carotid artery stenting in carotid near-occlusion.

MATERIALS AND METHODS

A retrospective data base review was performed from January 2010 to December 2018 to identify patients who underwent carotid endarterectomy or carotid artery stenting for symptomatic ICA near-occlusion and had 1-month clinical and imaging follow-up with carotid sonography. The medical records and imaging studies of patients with ICA near-occlusion were selected for analysis.

RESULTS

Forty-five patients met the criteria for ICA near-occlusion, of whom 39 were included in the study, given insufficient 1-month follow-up on 6 patients. Of the 39 patients, 25 underwent carotid endarterectomy and 14 underwent carotid artery stenting. All patients had technically successful immediate revascularization of the ICA. Most (33 of 39) had 1-year follow-up postoperatively. Patients with carotid artery stenting had 20% restenosis and 79% vessel maturation rates, while patients with carotid endarterectomy had 17.4% restenosis and 84% vessel maturation. There was no significant difference in periprocedural complication rates between the 2 procedures.

CONCLUSIONS

Carotid artery stenting shows similar outcomes in restenosis and vessel maturation rates compared with carotid endarterectomy for ICA near-occlusion. There were no major differences between the 2 treatments in clinical outcomes or periprocedural complications. Carotid artery stenting is a revascularization option for carotid near-occlusion if the patient is considered at high risk for carotid endarterectomy.

摘要

背景与目的

颈动脉近闭塞定义为颈内动脉严重狭窄,伴远端血管壁部分或完全塌陷。评估颈动脉血运重建的主要研究排除了颈动脉近闭塞患者。鉴于文献中数据有限,我们试图评估颈动脉内膜切除术和颈动脉支架置入术治疗颈动脉近闭塞的安全性。

材料与方法

回顾性分析 2010 年 1 月至 2018 年 12 月期间因症状性颈内动脉近闭塞而行颈动脉内膜切除术或颈动脉支架置入术的患者的临床和影像学资料。所有患者均在术后 1 个月行颈动脉超声检查进行随访。对符合条件的患者进行分析。

结果

45 例患者符合颈内动脉近闭塞标准,其中 6 例患者因术后 1 个月随访时间不足而被排除在外,其余 39 例患者被纳入研究。39 例患者中,25 例行颈动脉内膜切除术,14 例行颈动脉支架置入术。所有患者的颈内动脉均成功实现即刻血运重建。大多数(39 例中的 33 例)在术后 1 年进行了随访。颈动脉支架置入术患者的再狭窄率为 20%,血管成熟率为 79%,颈动脉内膜切除术患者的再狭窄率为 17.4%,血管成熟率为 84%。两种手术的围手术期并发症发生率无显著差异。

结论

颈动脉支架置入术治疗颈内动脉近闭塞的再狭窄率和血管成熟率与颈动脉内膜切除术相似。两种治疗方法在临床结局和围手术期并发症方面无显著差异。对于颈动脉内膜切除术高危患者,颈动脉支架置入术是一种可行的血运重建选择。

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