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连续性腹膜透析治疗大鼠急性实验性胰腺炎。I. 对生存长度和生存率的影响

Continuous peritoneal dialysis as treatment of acute experimental pancreatitis in the rat. I. Effect on length and rate of survival.

作者信息

Lankisch P G, Koop H, Winckler K, Schmidt H

出版信息

Dig Dis Sci. 1979 Feb;24(2):111-6. doi: 10.1007/BF01324737.

Abstract

Continuous peritoneal dialysis significantly prolonged mean length of survival and reduced lethality rate of taurocholate-induced pancreatitis in the rat. The effect was improved by compensating protein loss due to pancreatitis and dialysis treatment. The beneficial effect of intravenous albumin treatment was enhanced when combined with dialysis treatment. Using hypothermic dialysate or adding aprotinin intraperitoneally had no additional effect.

摘要

持续腹膜透析显著延长了牛磺胆酸盐诱导的大鼠胰腺炎的平均存活时间,并降低了致死率。通过补充胰腺炎和透析治疗导致的蛋白质损失,这种效果得到了改善。静脉注射白蛋白治疗与透析治疗联合使用时,其有益效果得到增强。使用低温透析液或腹腔内添加抑肽酶没有额外效果。

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