Echetebu Z O, Cox T M, Moss D W
Department of Chemical Pathology, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
Clin Chem. 1987 Oct;33(10):1832-6.
The immunological similarity between human tartrate-resistant acid phosphatase (EC 3.1.3.2) and porcine uteroferrin previously reported for the isoenzyme from spleens of patients with leukemic reticuloendotheliosis (Ketcham et al., J Biol Chem 1985;260:5768-76) has been confirmed for partly purified acid phosphatase found in the spleen of a patient with Gaucher's disease, and for the corresponding isoenzyme in other tissues and serum. Anti-uteroferrin antibodies raised in rabbits have been used to demonstrate the feasibility of their application in an immunoassay for tartrate-resistant acid phosphatase in serum.
先前报道的白血病性网状内皮细胞增多症患者脾脏中分离出的同工酶，其人类抗酒石酸酸性磷酸酶（EC 3.1.3.2）与猪子宫铁蛋白之间的免疫学相似性，已在一名戈谢病患者脾脏中部分纯化的酸性磷酸酶以及其他组织和血清中的相应同工酶中得到证实。用兔制备的抗子宫铁蛋白抗体已用于证明其在血清抗酒石酸酸性磷酸酶免疫测定中的应用可行性。
