峰值收缩期纵向旋转：二维斑点追踪超声心动图检测 2 型糖尿病患者左心室收缩功能的新工具。

Peak systolic longitudinal rotation: a new tool for detecting left ventricular systolic function in patients with type 2 diabetes mellitus by two-dimensional speckle tracking echocardiography.

机构信息

Department of Echocardiography, The Affiliated Changzhou No.2 People's Hospital with Nanjing Medical University, Changzhou, 213003, China.

Department of Cardiology, Weifang Traditional Chinese Hospital, Weifang, 261046, China.

出版信息

BMC Cardiovasc Disord. 2019 Jun 7;19(1):137. doi: 10.1186/s12872-019-1119-y.

BACKGROUND

Type 2 diabetes mellitus (T2DM) is one of the most prevalent cardiac and cerebrovascular risk factors. The study aimed to find a new way to investigate left ventricle (LV) systolic dysfunction in T2DM patients using two-dimensional speckle tracking echocardiography (2D-STE).

METHODS

Fifty-one untreated T2DM patients and 52 normal control subjects were enrolled for the research. Apical four-chamber view was acquired by two-dimensional echocardiography. Segmental and global peak systolic longitudinal rotation (PSLR) degrees were measured by the software of EchoPAC.

RESULTS

In T2DM patients, global PSLR prominently rotated clockwise, while in normal subjects, global PSLR degrees were so small and almost had no PSLR. HBA1c negatively correlated with apex and global PSLR, that is, T2DM patients with higher HBA1c had a larger clockwise apex and global PSLR. ROC analysis showed that PSLR could detect the accuracy of LV systolic dysfunction.

CONCLUSION

Cardiac clockwise global PSLR was found in T2DM patients. The cardiac contractile function in T2DM patients was impaired. The new tool of PSLR can conveniently detect cardiac systolic dysfunction in T2DM patients. HBA1c could predict systolic dysfunction in T2DM patients.

背景

2 型糖尿病（T2DM）是最常见的心脏和脑血管危险因素之一。本研究旨在寻找一种使用二维斑点追踪超声心动图（2D-STE）评估 T2DM 患者左心室（LV）收缩功能障碍的新方法。

方法

研究纳入了 51 例未经治疗的 T2DM 患者和 52 例正常对照者。通过二维超声心动图获取心尖四腔心切面。通过 EchoPAC 软件测量节段和整体收缩期纵向旋转峰值（PSLR）度。

结果

T2DM 患者的整体 PSLR 明显顺时针旋转，而在正常对照组中，整体 PSLR 度非常小，几乎没有 PSLR。HBA1c 与心尖和整体 PSLR 呈负相关，即 HBA1c 较高的 T2DM 患者心尖和整体 PSLR 的顺时针旋转幅度更大。ROC 分析表明，PSLR 可以检测 LV 收缩功能障碍的准确性。