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轻度和重度烧伤后 5-7 年的健康相关生活质量:一项多中心横断面研究。

Health related quality of life 5-7 years after minor and severe burn injuries: a multicentre cross-sectional study.

机构信息

Erasmus MC, University Medical Center Rotterdam, Department of Public Health, Rotterdam, The Netherlands; Association of Dutch Burn Centres, Maasstad Hospital, Rotterdam, The Netherlands; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Plastic, Reconstructive and Hand Surgery, Amsterdam Movement Sciences, Amsterdam, The Netherlands.

Erasmus MC, University Medical Center Rotterdam, Department of Public Health, Rotterdam, The Netherlands.

出版信息

Burns. 2019 Sep;45(6):1291-1299. doi: 10.1016/j.burns.2019.03.017. Epub 2019 Jun 5.

Abstract

INTRODUCTION

Burn injury can affect health-related quality of life (HRQL). Knowledge concerning long-term HRQL in burn patients is limited. Therefore our aim was to evaluate long-term HRQL and to study predictors of impaired long-term HRQL.

METHODS

All adults with a length of stay (LOS) of ≥1 day (2011-2012) were invited. Also, adults with severe burns, i.e., >20% total body surface area (TBSA) burned or TBSA full thickness>5% (2010-2013) were invited. Participants completed the EuroQol(EQ)-5 D-5L + C and visual analogue scale (EQ-VAS) 5-7 years after burns.

RESULTS

This study included 256 patients (mean %TBSA 10%); 187 patients with minor burns and 69 patients with severe burns. Mean EQ-5D summary was 0.90 and EQ-VAS 83.2 in the minor burn patients, and 0.79 and 78.1 in the severe burn patients. Some problems in at least one dimension were experienced by 81% of patients with severe burns and 45% of those with minor burns. However, a minority reported severe or extreme problems; 15% of those with severe burns and 6% of those with minor burns. Patients with severe burns reported significantly more problems, except for anxiety/depression. In both patient groups most problems were reported on pain/discomfort. Length of hospital stay, gender and age were associated with lower long-term HRQL (EQ-VAS) in multivariate analyses, whereas only length of stay was associated with a lower summary score.

CONCLUSIONS

The majority of patients experienced some problems with HRQL 5-7 years post burn. This emphasizes that burns can have a negative impact on an individual's HRQL, particularly in more severely burned patients, that persists for years. The HRQL dimensions most frequently affected include pain/discomfort and anxiety/depression. Patients with a prolonged hospital stay, females and older patients are at higher risk of poor HRQL in the long-term.

摘要

简介

烧伤会影响健康相关生活质量(HRQL)。关于烧伤患者长期 HRQL 的知识有限。因此,我们的目的是评估长期 HRQL,并研究影响长期 HRQL 的因素。

方法

邀请所有住院时间(LOS)≥1 天(2011-2012 年)的成年人参加。还邀请了严重烧伤患者,即 >20%的总体表面积(TBSA)烧伤或 TBSA 全层厚度>5%(2010-2013 年)的患者。烧伤后 5-7 年,参与者完成了欧洲生活质量五维问卷(EQ-5D)5 级量表+简短补充量表(EQ-VAS)。

结果

这项研究共纳入 256 例患者(平均 TBSA 为 10%);187 例轻度烧伤患者和 69 例严重烧伤患者。轻度烧伤患者的 EQ-5D 总评分平均为 0.90,EQ-VAS 为 83.2;严重烧伤患者的 EQ-5D 总评分平均为 0.79,EQ-VAS 为 78.1。严重烧伤患者至少有一个维度存在问题的比例为 81%,轻度烧伤患者为 45%。然而,少数患者报告存在严重或极度问题;严重烧伤患者占 15%,轻度烧伤患者占 6%。严重烧伤患者报告的问题明显更多,除了焦虑/抑郁。在这两个患者组中,大多数问题都报告在疼痛/不适方面。多变量分析显示,住院时间、性别和年龄与长期 HRQL(EQ-VAS)较低相关,而只有住院时间与较低的总分相关。

结论

烧伤后 5-7 年,大多数患者经历了一些与 HRQL 相关的问题。这强调了烧伤会对个人的 HRQL 产生负面影响,尤其是在烧伤更严重的患者中,这种影响会持续多年。受影响最频繁的 HRQL 维度包括疼痛/不适和焦虑/抑郁。住院时间延长、女性和老年患者在长期内发生 HRQL 不良的风险更高。

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