意大利西西里岛和撒丁岛的炎症性肠病的流行率和发病率：基于卫生信息系统的报告。

Prevalence and incidence of inflammatory bowel disease in two Italian islands, Sicily and Sardinia: A report based on health information systems.

机构信息

IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy.

Gastroenterology Unit, "G. Brotzu" Hospital, Cagliari, Italy.

出版信息

Dig Liver Dis. 2019 Sep;51(9):1270-1274. doi: 10.1016/j.dld.2019.05.017. Epub 2019 Jun 5.

DOI:10.1016/j.dld.2019.05.017

PMID:31176630

Abstract

BACKGROUND

Few epidemiological data about inflammatory bowel disease (IBD) in Italy are available.

AIMS

To estimate IBD prevalence and incidence in two Italian regions - Sicily and Sardinia - using regional health information systems.

METHODS

Data from hospital discharges and disease-specific payment exemptions register were retrieved and underwent record-linkage procedures. Standardized prevalence and incidence were calculated as rates per 100,000 inhabitants.

RESULTS

In Sicily, during the year 2013, the overall IBD incidence rate was 27 per 100,000 inhabitants, while the incidence rate of Crohn's disease (CD) was 16 for males and 13 for females, and the incidence of ulcerative colitis (UC) was 15 and 11 for males and females, respectively. At the date of December 31st, 2013, the standardized prevalence rate of IBD was estimated at 300 cases per 100,000 inhabitants. In Sardinia, during the period 2008-2010, the average IBD incidence rate per 100,000 was 15, with an incidence rate of 5 per 100,000 for CD, and 10 per 100,000 for UC, while the standardized prevalence rate of IBD was estimated at 187 cases per 100,000 inhabitants.

CONCLUSIONS

The particularly high incidence of CD in Sicily, and the marked difference of IBD occurrence between the two islands deserve future investigations.

摘要

背景

意大利关于炎症性肠病（IBD）的流行病学数据很少。

目的

利用区域卫生信息系统评估意大利两个地区（西西里岛和撒丁岛）的 IBD 患病率和发病率。

方法

检索了来自医院出院和疾病特定支付豁免登记处的数据，并进行了记录链接程序。以每 10 万人为单位计算标准化患病率和发病率。

结果

在西西里岛，2013 年，IBD 的总发病率为每 10 万人 27 例，男性 CD 的发病率为 16 例，女性为 13 例，UC 的发病率为 15 例，男性为 11 例，女性为 11 例。截至 2013 年 12 月 31 日，IBD 的标准化患病率估计为每 10 万人 300 例。在撒丁岛，2008 年至 2010 年期间，IBD 的平均发病率为每 10 万人 15 例，CD 的发病率为每 10 万人 5 例，UC 的发病率为每 10 万人 10 例，IBD 的标准化患病率估计为每 10 万人 187 例。