Trallori G, Palli D, Saieva C, Bardazzi G, Bonanomi A G, d'Albasio G, Galli M, Vannozzi G, Milla M, Tarantino O, Renai F, Messori A, Amorosi A, Pacini F, Morettini A
U.O. di Gastroenterologia, CSPO, Florence, Italy.
Scand J Gastroenterol. 1996 Sep;31(9):892-9. doi: 10.3109/00365529609051998.
In the group of inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD) are considered to be more frequent in Western countries and in areas with a high socioeconomic development but relatively infrequent in southern Europe. Sporadic reports have indicated a lower incidence and a milder course of the disease in Mediterranean countries. Although conclusive data on this point are still lacking, recent reports suggest an increase in both incidence and prevalence rates.
The incidence of UC and CD during the period January 1978 to December 1992 and their prevalence on 31 December 1992 were estimated in the 15-year-old population of the metropolitan area of Florence. Clinical, demographic, and follow-up information was collected for all identified IBD patients.
A total of 796 residents (345 females and 454 males) were newly diagnosed as having IBD during the study period. Of these 593 had UC and 203 CD. The age-standardized incidence rates, calculated for each of five 3-year consecutive periods, rose from 3.8 (in 1978-80) to 9.6 per 100,000 person-years (in 1990-92) for UC and from 1.9 (in 1978-80) to 3.4 (in 1990-92) for CD. Both trends were statistically significant. The prevalence estimated on 31 December 1992 was 121.0 and 40.0 per 100,000 inhabitants for UC and CD, respectively.
Our results confirm that IBD incidence rates and prevalence in this area of central Italy are currently comparable with those reported in northern Europe. These data are necessary for planning adequate health care services for IBD patients.
在炎症性肠病（IBD）群体中，溃疡性结肠炎（UC）和克罗恩病（CD）在西方国家以及社会经济高度发达地区更为常见，但在南欧相对少见。零星报告表明，在地中海国家该疾病的发病率较低且病程较轻。尽管在这一点上仍缺乏确凿数据，但最近的报告显示发病率和患病率均有所上升。
对佛罗伦萨市区15岁人群在1978年1月至1992年12月期间的UC和CD发病率以及1992年12月31日的患病率进行了估算。收集了所有确诊的IBD患者的临床、人口统计学和随访信息。
在研究期间，共有796名居民（345名女性和454名男性）新诊断为患有IBD。其中593人患有UC，203人患有CD。按连续五个3年时间段分别计算的年龄标准化发病率，UC从每10万人年3.8（1978 - 1980年）升至9.6（1990 - 1992年），CD从每10万人年1.9（1978 - 1980年）升至3.4（1990 - 1992年）。两种趋势均具有统计学意义。1992年12月31日估算的UC和CD患病率分别为每10万居民121.0和40.0。
我们的结果证实，意大利中部该地区的IBD发病率和患病率目前与北欧报告的水平相当。这些数据对于为IBD患者规划适当的医疗服务是必要的。
