Varnier Giulia C, Ciurtin Coziana
Clinical Research Fellow in Adolescent Rheumatology, Department of Rheumatology, University London College, London WC1E 6BT.
Consultant in Adolescent and Adult Rheumatology, Department of Rheumatology, University London College Hospital NHS Trust, London.
Br J Hosp Med (Lond). 2019 Jun 2;80(6):338-342. doi: 10.12968/hmed.2019.80.6.338.
Juvenile idiopathic arthritis, juvenile systemic lupus erythematosus and juvenile dermatomyositis are rare, chronic, multi-systemic rheumatic disorders that can be associated with significant morbidity, not only during childhood, but lifelong. Dedicated disease activity and damage assessment tools are essential to guide clinical management and perform multicentre clinical trials to ensure the best possible care and outcome for children with rheumatic diseases using an evidence-based, treat-to-target approach. This article summarizes the outcome measures most commonly used in paediatric rheumatology.
幼年特发性关节炎、幼年系统性红斑狼疮和幼年皮肌炎是罕见的慢性多系统风湿性疾病,不仅在儿童期,而且在整个生命过程中都可能伴有严重的发病率。专门的疾病活动和损伤评估工具对于指导临床管理以及开展多中心临床试验至关重要,以便采用循证治疗达标方法,为患有风湿性疾病的儿童确保尽可能最佳的治疗和预后。本文总结了儿科风湿病中最常用的转归指标。