Moran K T, McEntee G, Jones B, Hone R, Duignan J P, O'Malley E
St Michael's Hospital, Dunlaoire.
Ann R Coll Surg Engl. 1987 Sep;69(5):235-6.
The effect of subcutaneous catheter tunnelling on the incidence of catheter sepsis and on catheter life span in the absence of a nutrition team was determined in a prospective controlled clinical trial. Eighty one patients who received 92 courses of parenteral nutrition had 110 catheters inserted. Alternate catheters were tunnelled. Four patients who received parentheral nutrition for less than 48 hours were excluded from the study. Catheter related sepsis occurred in one tunnelled (1.8%) and 4 non-tunnelled catheters (7.6%) (P greater than 0.05 NS). Mean life span of tunnelled catheters was 21 days (range 5-37 days) compared to 12.6 days for non-tunnelled (range 3-19 days) (P less than 0.05). Six non-tunnelled catheters became displaced, a complication which did not occur with tunnelled catheters (P less than 0.01). In conclusion subcutaneous tunnelling of silicone catheters prolongs catheter life span but does not significantly influence catheter sepsis.
在一项前瞻性对照临床试验中，研究了在没有营养支持团队的情况下，皮下导管隧道技术对导管败血症发生率和导管使用寿命的影响。81例接受92疗程肠外营养的患者共插入110根导管，交替进行导管隧道技术处理。4例接受肠外营养不足48小时的患者被排除在研究之外。导管相关败血症在1根经隧道技术处理的导管中发生（1.8%），在4根未经隧道技术处理的导管中发生（7.6%）（P>0.05，无统计学差异）。经隧道技术处理的导管平均使用寿命为21天（范围5 - 37天），而未经隧道技术处理的导管为12.6天（范围3 - 19天）（P<0.05）。6根未经隧道技术处理的导管发生移位，而经隧道技术处理的导管未出现此并发症（P<0.01）。总之，硅胶导管的皮下隧道技术可延长导管使用寿命，但对导管败血症无显著影响。
