Abdullayev Ruslan, Yildirim Ercan, Celik Bulent, Topcu Sarica Leyla
Anesthesiology and Reanimation, Marmara University School of Medicine, İstanbul, TUR.
Anesthesiology and Reanimation, Gazi University School of Medicine, Ankara, TUR.
Cureus. 2019 Apr 2;11(4):e4365. doi: 10.7759/cureus.4365.
Background Analgesia nociception index (ANI) has been developed for real-time pain measurement during a surgical procedure under general anesthesia. The index is based on heart rate variability and constitutes a measure of parasympathetic tone. In this paper, we hypothesized that this index could be used as a tool to investigate the process of emotional regulation of a human subject. Materials and methods Twenty adult volunteers were recruited for the study, wherein ANI response to the emotional stimulus was evaluated. An emotional stimulus was obtained through a 60-second music sound record from the song "Ala Gözlerini Sevdiğim Dilber," performed by the Turkish rock band Badem. ANI measurements were obtained before the song presentation (T), at the end of the record presentation (T0), and each minute thereafter until the end of the five-minute observation (T1-T5). Results Twenty participants were investigated; 10 males and 10 females. The mean age of the participants was 17.0 ± 0.9 (min: 16, max: 20). ANI measurements were significantly lower in T0 and T3 compared with T ( = 0.009). The differences between other values were not statistically significant. Conclusion ANI can be used for assessment of parasympathetic changes related to the emotional state of conscious patients.
镇痛伤害感受指数（ANI）已被开发用于在全身麻醉下的外科手术过程中进行实时疼痛测量。该指数基于心率变异性，是副交感神经张力的一种度量。在本文中，我们假设该指数可作为一种工具来研究人类受试者的情绪调节过程。材料与方法：招募了20名成年志愿者参与该研究，其中评估了ANI对情绪刺激的反应。通过土耳其摇滚乐队巴德姆（Badem）演唱的歌曲《Ala Gözlerini Sevdiğim Dilber》的60秒音乐录音获得情绪刺激。在歌曲播放前（T）、录音播放结束时（T0）以及此后直到五分钟观察结束（T1 - T5）的每分钟进行ANI测量。结果：对20名参与者进行了调查，其中10名男性和10名女性。参与者的平均年龄为17.0 ± 0.9（最小：16，最大：20）。与T相比，T0和T3时的ANI测量值显著更低（P = 0.009）。其他值之间的差异无统计学意义。结论：ANI可用于评估与清醒患者情绪状态相关的副交感神经变化。
