Odgers Harrison L, Taylor Rebecca A M, Balendran Jananie, Benness Christopher, Ludlow Joanne
Royal Prince Alfred Hospital, Sydney, NSW, Australia.
The University of Sydney, Sydney, NSW, Australia.
Case Rep Womens Health. 2019 Apr 29;22:e00120. doi: 10.1016/j.crwh.2019.e00120. eCollection 2019 Apr.
Caesarean scar pregnancy is an uncommon form of ectopic pregnancy characterized by implantation into the site of a caesarean scar. Common clinical features include vaginal bleeding and abdominal pain; however, a significant proportion of cases are asymptomatic. The primary diagnostic modality is transvaginal ultrasound. There is no current consensus on best-practice management.
A 36-year-old woman, G7P2, presented to an early-pregnancy service with vaginal spotting and an ultrasound scan demonstrating a live caesarean scar ectopic pregnancy at 8 + 5 weeks' gestation. On examination she was hemodynamically stable with a soft abdomen. She was advised to have dilation and curettage (D&C) under ultrasound guidance; however, she was concerned that she might require more extensive surgery, such as a hysterectomy and so requested non-surgical management. On day 1 she underwent ultrasound-guided embryocide with lignocaine followed by inpatient multi-dose systemic methotrexate. Her beta-human gonadotrophic hormone level decreased. Repeat ultrasound on day 18 demonstrated a persistent caesarean scar ectopic pregnancy with increased vascularity, and so uterine artery embolization (UAE) was performed with a view to D&C the following day. This plan was altered to expectant management with ongoing follow-up by a different clinician who had had previous success with UAE alone. On day 35 the patient presented with life-threatening vaginal bleeding that required an emergency total abdominal hysterectomy.
Caesarean scar pregnancies are uncommon. Multiple treatment strategies have been employed, with variable degrees of success. Further research into risk stratification and management are needed to guide clinician and patient decision making.
剖宫产瘢痕妊娠是一种少见的异位妊娠形式,其特征为妊娠物着床于剖宫产瘢痕部位。常见临床特征包括阴道出血和腹痛;然而,相当一部分病例无症状。主要诊断方式为经阴道超声检查。目前对于最佳治疗方案尚无共识。
一名36岁女性,孕7产2,因阴道少量出血就诊于早孕门诊,超声检查显示孕8⁺⁵周活胎剖宫产瘢痕异位妊娠。检查时她血流动力学稳定,腹部柔软。建议她在超声引导下行刮宫术(D&C);然而,她担心可能需要更广泛的手术,如子宫切除术,因此要求非手术治疗。第1天,她在超声引导下用利多卡因进行胚胎灭活,随后住院接受多剂量全身甲氨蝶呤治疗。她的β-人绒毛膜促性腺激素水平下降。第18天复查超声显示剖宫产瘢痕异位妊娠持续存在且血管增多,因此进行了子宫动脉栓塞术(UAE),以期次日行刮宫术。该计划改为期待治疗,由另一位曾单独成功实施UAE的医生进行持续随访。第35天,患者出现危及生命 的阴道出血,需要紧急行全腹子宫切除术。
剖宫产瘢痕妊娠并不常见。已采用多种治疗策略,成功率各不相同。需要对风险分层和治疗进行进一步研究,以指导临床医生和患者的决策。