性别影响癫痫患者后头部基本α节律的频率。
Sex influences the frequency of the posterior basic alpha rhythm in patients with epilepsy.
作者信息
Stephani C, Khan A, Koubeissi M, Paulus W
机构信息
Department for Clinical Neurophysiology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
Institute for Biomagnetism and Biosignalanalysis, University of Münster, Malmedyweg 15, 48149 Münster, Germany.
出版信息
Clin Neurophysiol Pract. 2019 Apr 26;4:85-89. doi: 10.1016/j.cnp.2019.04.002. eCollection 2019.
OBJECTIVE
To determine effects of sex, epilepsy and epilepsy medication on the posterior basic alpha rhythm.
METHODS
We reviewed the routine EEGs of 160 subjects, including 60 individuals with focal epilepsy, 60 with generalized epilepsy, and 40 healthy controls, measured the mean alpha frequencies of each person and applied a univariate three-factorial analysis of variance.
RESULTS
Women have a significantly faster posterior basic rhythm as compared to men. Sex was the only independent factor influencing the posterior basic rhythm in this cohort. Additionally, we detected an interaction with intake of lamotrigine and idiopathic generalized epilepsy both increasing the basic alpha frequency in the group of female subjects only.
CONCLUSION
Sex was the main determinant of the posterior basic alpha frequency in our cohort.
SIGNIFICANCE
Sex can influence the frequency of the posterior basic alpha rhythm.
目的
确定性别、癫痫及抗癫痫药物对后部基本α节律的影响。
方法
我们回顾了160名受试者的常规脑电图，其中包括60名局灶性癫痫患者、60名全身性癫痫患者以及40名健康对照者，测量了每个人的平均α频率，并进行单因素三因素方差分析。
结果
与男性相比，女性的后部基本节律明显更快。在该队列中，性别是影响后部基本节律的唯一独立因素。此外，我们还检测到拉莫三嗪的摄入与特发性全身性癫痫之间存在相互作用，二者均仅在女性受试者组中增加了基本α频率。
结论
在我们的队列中，性别是后部基本α频率的主要决定因素。
意义
性别可影响后部基本α节律的频率。
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