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[口服冻干活菌对小鼠肠道生态系统的干扰]

[Interference of the intestinal ecosystem of mice in the oral administration of lyophilized live bacteria].

作者信息

Gismondo M R, Pappalardo C, Fichera G, Nicoletti G

机构信息

Istituto di Microbiologia, Università di Catania.

出版信息

G Batteriol Virol Immunol. 1986 Jan-Jun;79(1-6):113-23.

PMID:3119409
Abstract

Oral vaccines mode by living or killed bacteria are commonly used to restore normal intestinal flora; it's not well know, however, which bacteria play the leading part in this ecosystem. In the present paper Authors have intended to compare the effectiveness of an oral vaccine, made by Bifidobacterium bifidus and Lactobacillus acidofilus, with another of similar use, made by Enterococci, to increase the mouse resistance to lethal Salmonella enteritidis infections. According to collected microbiological data and M.E.S. photos, the association Bifidob./Lactobac. is more effective than Enterococci to enhance resistance to the experimental infection.

摘要

由活细菌或灭活细菌制成的口服疫苗常用于恢复正常肠道菌群;然而,目前尚不清楚在这个生态系统中哪种细菌起主要作用。在本文中,作者旨在比较由双歧杆菌和嗜酸乳杆菌制成的口服疫苗与另一种由肠球菌制成的类似用途的口服疫苗在提高小鼠对致死性肠炎沙门氏菌感染的抵抗力方面的有效性。根据收集到的微生物学数据和M.E.S.照片,双歧杆菌/乳杆菌组合在增强对实验性感染的抵抗力方面比肠球菌更有效。

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