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[口服疫苗对小鼠实验性感染的保护作用及其与抗生素联合使用时的协同作用]

[Protection against experimental infections in mice by an oral vaccine and its combined role when administered with antibiotics].

作者信息

Gismondo M R, Lo Bue A M, Chisari G, Cosenza C, Stivala F

机构信息

Istituto di Microbiologia, Università di Catania.

出版信息

G Batteriol Virol Immunol. 1987 Jan-Dec;80(1-12):177-81.

PMID:3334311
Abstract

Immunomodulator with significantly modify the immunologic response of the host. The AA. studied the immunologic profile of an oral vaccine to protect the experimental infection in mice and its effect when it was administered with antibiotics. The mice infected with S. enteritidis were protected by the vaccine administered. Also in the group of mice treated with a vaccine and antibiotic combination, the mortality rate was lower than in the untreated groups.

摘要

免疫调节剂可显著改变宿主的免疫反应。研究人员研究了一种口服疫苗的免疫特征,以保护小鼠免受实验性感染,以及该疫苗与抗生素联合使用时的效果。感染肠炎沙门氏菌的小鼠通过接种该疫苗得到了保护。在疫苗和抗生素联合治疗的小鼠组中,死亡率也低于未治疗组。

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G Batteriol Virol Immunol. 1987 Jan-Dec;80(1-12):177-81.
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