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HFpEF 和 HFrEF 中的肺动脉高压和右心室重构。

Pulmonary hypertension and right ventricular remodeling in HFpEF and HFrEF.

机构信息

Division of Cardiology, Fondazione I.R.C.C.S. Policlinico San Matteo, Pavia, Italy.

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

Heart Fail Rev. 2020 Jan;25(1):85-91. doi: 10.1007/s10741-019-09810-4.

Abstract

Right ventricular function has long been neglected by heart failure specialists. We have now learnt that it is strongly associated with morbidity and mortality in all patients with heart failure, regardless of the degree of left ventricular dysfunction. Importantly, right ventricular function is tightly linked with pulmonary hypertension, and only a thorough understanding of how the right ventricle couples with the pulmonary circulation can provide an improved knowledge of the pathophysiology and possibly a more efficient treatment and a better prognosis in patients with heart failure.

摘要

右心室功能长期以来一直被心力衰竭专家所忽视。我们现在已经了解到,无论左心室功能障碍程度如何,它与所有心力衰竭患者的发病率和死亡率都密切相关。重要的是,右心室功能与肺动脉高压密切相关,只有深入了解右心室与肺循环的耦联方式,才能更好地了解心力衰竭的病理生理学,并可能提供更有效的治疗和更好的预后。

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