Imaging Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Heart and Vascular Institute and Imaging Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Prog Nucl Magn Reson Spectrosc. 2021 Feb;122:11-22. doi: 10.1016/j.pnmrs.2020.10.001. Epub 2020 Nov 6.
Quantitative cardiac magnetic resonance has emerged in recent years as an approach for evaluating a range of cardiovascular conditions, with T and T mapping at the forefront of these developments. Cardiac Magnetic Resonance Fingerprinting (cMRF) provides a rapid and robust framework for simultaneous quantification of myocardial T and T in addition to other tissue properties. Since the advent of cMRF, a number of technical developments and clinical validation studies have been reported. This review provides an overview of cMRF, recent technical developments, healthy subject and patient studies, anticipated technical improvements, and potential clinical applications. Recent technical developments include slice profile and pulse efficiency corrections, improvements in image reconstruction, simultaneous multislice imaging, 3D whole-ventricle imaging, motion-resolved imaging, fat-water separation, and machine learning for rapid dictionary generation. Future technical developments in cMRF, such as B and B field mapping, acceleration of acquisition and reconstruction, imaging of patients with implanted devices, and quantification of additional tissue properties are also described. Potential clinical applications include characterization of infiltrative, inflammatory, and ischemic cardiomyopathies, tissue characterization in the left atrium and right ventricle, post-cardiac transplantation assessment, reduction of contrast material, pre-procedural planning for electrophysiology interventions, and imaging of patients with implanted devices.
近年来，定量心脏磁共振已成为评估多种心血管疾病的一种方法，其中 T1 和 T2 mapping 处于这些发展的前沿。心脏磁共振指纹技术（cMRF）为同时定量心肌 T1 和 T2 以及其他组织特性提供了一种快速而稳健的框架。自 cMRF 问世以来，已经有许多技术发展和临床验证研究的报道。本综述概述了 cMRF 的基本原理、近期技术发展、健康受试者和患者研究、预期的技术改进以及潜在的临床应用。最近的技术发展包括了层面轮廓和脉冲效率校正、图像重建改进、多层面同时成像、3D 全心室成像、运动分辨成像、水脂分离以及快速字典生成的机器学习。cMRF 的未来技术发展，如 B0 和 B1 场映射、采集和重建的加速、植入设备患者的成像以及其他组织特性的定量等也进行了描述。潜在的临床应用包括浸润性、炎症性和缺血性心肌病的特征描述、左心房和右心室的组织特征描述、心脏移植后的评估、对比剂的减少、电生理介入的术前规划以及植入设备患者的成像。
