• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

力量训练对2型糖尿病患者血浆同型半胱氨酸水平的影响。

Effect of Strength Training on Plasma Levels of Homocysteine in Patients with Type 2 Diabetes.

作者信息

Silva Alexandre de Souza E, Lacerda Fábio Vieira, da Mota Maria Paula Gonçalves

机构信息

University of Trás-os-Montes and Alto Douro, Carrazeda de Ansiães, Portugal.

University Center of Itajubá, Itajubá, Brazil.

出版信息

Int J Prev Med. 2019 May 17;10:80. doi: 10.4103/ijpvm.IJPVM_313_17. eCollection 2019.

DOI:10.4103/ijpvm.IJPVM_313_17
PMID:31198515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6547780/
Abstract

BACKGROUND

The objective of this study was to analyze the effects of strength training on plasma homocysteine levels and cardiovascular risk factors in patients with type 2 diabetes.

METHODS

The sample consisted of 14 diabetic women with a mean age of 68 ± 6 years. Biochemical evaluations and anthropometric measurements were taken before and after training. Training sessions lasted 50 min and comprised three sets of 8-12 repetitions each. The established load was 60% of 1 repetition maximum.

RESULTS

After the training program, it was observed that the levels of homocysteine (average before 13.4 ± 2.9 and after 12.8 ± 3.3, = 0.40), very low-density lipoprotein (LDL) (average before 41.9 ± 17.0 and after 36.2 ± 11.8, = 0.47), total cholesterol (average before 214.4 ± 60.6 and after 190.2 ± 62.3, = 0.09), triglycerides (average before 209.3 ± 85.4 and after 181.5 ± 59.2, = 0.47), and blood glucose (average before 123.5 ± 30.4 and after 110.1 ± 24.7, = 0.26) showed no significant changes, but the LDL (average before 129.1 ± 63.4 and after 95.7 ± 53.3, = 0.04), high-density lipoprotein (average before 43.2 ± 12.0 and after 58.2 ± 15.6, = 0.01), lean mass (average before 41.1 ± 5.7 and after 42.8 ± 5.4, = 0.008), fat mass (average before 31.4 ± 8.8 and after 29.7 ± 8.5, = 0.001), and percentage fat (average before 42.6 ± 4.0 and after 40.3 ± 4.6, = 0.000) showed significant changes.

CONCLUSIONS

This study concluded that strength training does not improve homocysteine levels, but help to improve the lipoprotein profile in type 2 diabetic patients.

摘要

背景

本研究的目的是分析力量训练对2型糖尿病患者血浆同型半胱氨酸水平及心血管危险因素的影响。

方法

样本包括14名平均年龄为68±6岁的糖尿病女性。在训练前后进行生化评估和人体测量。训练课程持续50分钟,每组包括8 - 12次重复动作,共三组。设定的负荷为1次最大重复量的60%。

结果

训练计划结束后,观察到同型半胱氨酸水平(训练前平均为13.4±2.9,训练后为12.8±3.3,P = 0.40)、极低密度脂蛋白(LDL)(训练前平均为41.9±17.0,训练后为36.2±11.8,P = 0.47)、总胆固醇(训练前平均为214.4±60.6,训练后为190.2±62.3,P = 0.09)、甘油三酯(训练前平均为209.3±85.4,训练后为181.5±59.2,P = 0.47)和血糖(训练前平均为123.5±30.4,训练后为110.1±24.7,P = 0.26)均无显著变化,但LDL(训练前平均为129.1±63.4,训练后为95.7±53.3,P = 0.04)、高密度脂蛋白(训练前平均为43.2±12.0,训练后为58.2±15.6,P = 0.01)、去脂体重(训练前平均为41.1±5.7,训练后为42.8±5.4,P = 0.008)、脂肪量(训练前平均为31.4±8.8,训练后为29.7±8.5,P = 0.001)和脂肪百分比(训练前平均为42.6±4.0,训练后为40.3±4.6,P = 0.000)有显著变化。

结论

本研究得出结论,力量训练不能改善同型半胱氨酸水平,但有助于改善2型糖尿病患者的脂蛋白谱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8f2/6547780/aa6483ea36d5/IJPVM-10-80-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8f2/6547780/aa6483ea36d5/IJPVM-10-80-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8f2/6547780/aa6483ea36d5/IJPVM-10-80-g001.jpg

相似文献

1
Effect of Strength Training on Plasma Levels of Homocysteine in Patients with Type 2 Diabetes.力量训练对2型糖尿病患者血浆同型半胱氨酸水平的影响。
Int J Prev Med. 2019 May 17;10:80. doi: 10.4103/ijpvm.IJPVM_313_17. eCollection 2019.
2
Total homocysteine levels relation with chronic complications of diabetes, body composition, and other cardiovascular risk factors in a population of patients with diabetes mellitus type 2.2型糖尿病患者群体中总同型半胱氨酸水平与糖尿病慢性并发症、身体成分及其他心血管危险因素的关系
J Diabetes Complications. 2005 Jan-Feb;19(1):42-6. doi: 10.1016/j.jdiacomp.2003.12.003.
3
The effect of aerobic vs. resistance training on plasma homocysteine in individuals with type 2 diabetes.有氧运动与抗阻训练对2型糖尿病患者血浆同型半胱氨酸水平的影响。
J Diabetes Metab Disord. 2020 Jul 31;19(2):1003-1009. doi: 10.1007/s40200-020-00596-z. eCollection 2020 Dec.
4
Elevated plasma homocysteine levels in gestational diabetes mellitus.妊娠期糖尿病患者血浆同型半胱氨酸水平升高。
Acta Obstet Gynecol Scand. 2004 Jun;83(6):543-7. doi: 10.1111/j.0001-6349.2004.00540.x.
5
Effects of endurance training and resistance training on plasma lipoprotein profiles in elderly women.耐力训练和抗阻训练对老年女性血浆脂蛋白谱的影响。
J Gerontol A Biol Sci Med Sci. 2002 Feb;57(2):B54-60. doi: 10.1093/gerona/57.2.b54.
6
Effects of Chair-Based, Low-Load Elastic Band Resistance Training on Functional Fitness and Metabolic Biomarkers in Older Women.基于椅子的低负荷弹性带阻力训练对老年女性功能性体能和代谢生物标志物的影响。
J Sports Sci Med. 2021 Mar 1;20(1):133-141. doi: 10.52082/jssm.2021.133. eCollection 2021 Mar.
7
Effects of high-intensity training on cardiovascular risk factors in premenopausal and postmenopausal women.高强度训练对绝经前和绝经后女性心血管危险因素的影响。
Am J Obstet Gynecol. 2017 Apr;216(4):384.e1-384.e11. doi: 10.1016/j.ajog.2016.12.017. Epub 2016 Dec 23.
8
Homocysteine and lipoprotein levels following resistance training in older adults.老年人进行抗阻训练后的同型半胱氨酸和脂蛋白水平。
Prev Cardiol. 2003 Fall;6(4):197-203. doi: 10.1111/j.1520-037x.2003.01723.x.
9
The Effect of 12-Week of Aerobic Training on Homocysteine, Lipoprotein A and Lipid Profile Levels in Sedentary Middle-aged Men.12周有氧运动训练对久坐不动的中年男性同型半胱氨酸、脂蛋白A及血脂水平的影响
Int J Prev Med. 2014 Aug;5(8):1060-6.
10
Changes in body composition and use of blood cholesterol lowering drugs predict changes in blood lipids during 12 weeks of resistance exercise training in old adults.在老年人进行12周抗阻运动训练期间,身体成分的变化以及降血脂药物的使用可预测血脂的变化。
Aging Clin Exp Res. 2014 Jun;26(3):287-92. doi: 10.1007/s40520-013-0172-0. Epub 2013 Dec 1.

引用本文的文献

1
Effect of different training modalities on lipid metabolism in patients with type ii diabetes mellitus: a network meta-analysis.不同训练方式对 2 型糖尿病患者脂代谢的影响:网状 Meta 分析。
Ann Med. 2024 Dec;56(1):2428432. doi: 10.1080/07853890.2024.2428432. Epub 2024 Nov 16.
2
The effect of physical activity on total homocysteine concentrations and cardiovascular risk in older Brazilian adults with type 2 diabetes.体育活动对患有2型糖尿病的巴西老年成年人总同型半胱氨酸浓度及心血管风险的影响。
J Diabetes Metab Disord. 2021 Feb 22;20(1):407-416. doi: 10.1007/s40200-021-00759-6. eCollection 2021 Jun.
3
The effect of aerobic vs. resistance training on plasma homocysteine in individuals with type 2 diabetes.

本文引用的文献

1
[Evaluation the American College of Cardiology and American Heart Association Predictive score for cardiovascular diseases].[评估美国心脏病学会和美国心脏协会心血管疾病预测评分]
Rev Med Chil. 2017 Mar;145(3):292-298. doi: 10.4067/S0034-98872017000300002.
2
The Effect of Acute Hyperglycemia on Muscular Strength, Power and Endurance.急性高血糖对肌肉力量、功率和耐力的影响。
Int J Exerc Sci. 2017 May 1;10(3):390-396. doi: 10.70252/SDBW3813. eCollection 2017.
3
Association between muscle function and body composition, vitamin D status, and blood glucose in postmenopausal women with type 2 diabetes.
有氧运动与抗阻训练对2型糖尿病患者血浆同型半胱氨酸水平的影响。
J Diabetes Metab Disord. 2020 Jul 31;19(2):1003-1009. doi: 10.1007/s40200-020-00596-z. eCollection 2020 Dec.
4
Undercarboxylated osteocalcin has no adverse effect on endothelial function in rabbit aorta or human vascular cells.非羧化骨钙素对兔主动脉内皮功能或人血管细胞没有不良影响。
J Cell Physiol. 2021 Apr;236(4):2840-2849. doi: 10.1002/jcp.30048. Epub 2020 Sep 16.
5
The Effect of an Atherogenic Diet and Acute Hyperglycaemia on Endothelial Function in Rabbits Is Artery Specific.致动脉粥样硬化饮食和急性高血糖对兔血管内皮功能的影响具有动脉特异性。
Nutrients. 2020 Jul 16;12(7):2108. doi: 10.3390/nu12072108.
2型糖尿病绝经后女性的肌肉功能与身体成分、维生素D状态及血糖之间的关联
Diabetes Metab Syndr. 2017 Dec;11 Suppl 2:S679-S684. doi: 10.1016/j.dsx.2017.04.025. Epub 2017 Apr 28.
4
Effects of Exercise on Vascular Function, Structure, and Health in Humans.运动对人体血管功能、结构和健康的影响。
Cold Spring Harb Perspect Med. 2018 Apr 2;8(4):a029819. doi: 10.1101/cshperspect.a029819.
5
Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients: A Meta-Analysis.老年2型糖尿病患者抗阻训练对血糖控制、肌肉力量和瘦体重的影响:一项荟萃分析
Diabetes Ther. 2017 Jun;8(3):459-473. doi: 10.1007/s13300-017-0258-3. Epub 2017 Apr 5.
6
Associations of Low-Intensity Resistance Training with Body Composition and Lipid Profile in Obese Patients with Type 2 Diabetes.低强度抗阻训练与2型糖尿病肥胖患者身体成分和血脂水平的关联
PLoS One. 2015 Jul 15;10(7):e0132959. doi: 10.1371/journal.pone.0132959. eCollection 2015.
7
Associations between lower extremity muscle mass and metabolic parameters related to obesity in Japanese obese patients with type 2 diabetes.日本2型糖尿病肥胖患者下肢肌肉量与肥胖相关代谢参数之间的关联。
PeerJ. 2015 May 5;3:e942. doi: 10.7717/peerj.942. eCollection 2015.
8
The Effect of 12-Week of Aerobic Training on Homocysteine, Lipoprotein A and Lipid Profile Levels in Sedentary Middle-aged Men.12周有氧运动训练对久坐不动的中年男性同型半胱氨酸、脂蛋白A及血脂水平的影响
Int J Prev Med. 2014 Aug;5(8):1060-6.
9
Effects of physical activity and training programs on plasma homocysteine levels: a systematic review.体育活动和训练计划对血浆同型半胱氨酸水平的影响:一项系统综述
Amino Acids. 2014 Aug;46(8):1795-804. doi: 10.1007/s00726-014-1741-z. Epub 2014 Apr 26.
10
The effects of resistance training on ApoB/ApoA-I ratio, Lp(a) and inflammatory markers in patients with type 2 diabetes.抗阻训练对 2 型糖尿病患者载脂蛋白 B/载脂蛋白 A-I 比值、脂蛋白(a)和炎症标志物的影响。
Endocrine. 2012 Dec;42(3):561-9. doi: 10.1007/s12020-012-9650-y. Epub 2012 Mar 11.