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一名老年患者中类似发热性全身炎症性疾病的钙晶体相关性关节病。

Calcium crystal-associated arthropathy mimicking a febrile systemic inflammatory disease in an elderly patient.

作者信息

Sousa Anna Paula Duque, Moura Carlos, da Hora Priscila Ribeiro, Santiago Mittermayer

机构信息

Service of Rheumatology of Santa Izabel Hospital, Praça Almeida Couto 500, Salvador, BA, Brazil.

Department of Internal Medicine, Bahiana School of Medicine and Public Health, Avenida Dom João VI 275, Brotas, Salvador, BA, Brazil.

出版信息

Oxf Med Case Reports. 2019 May 31;2019(5):omz030. doi: 10.1093/omcr/omz030. eCollection 2019 May.

DOI:10.1093/omcr/omz030
PMID:31198566
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6544428/
Abstract

Crystal formation and deposition in the joints is an important and common cause of acute arthritis. The disease may present with fever and systemic signs. In this report, we describe the case of a 70-year-old man, who presented with a sudden and incapacitating polyarthritis of large and small joints, fever, asthenia and leukocytosis. After extensive investigation, radiography of the joints showed the presence of chondrocalcinosis. A few days after the beginning of the treatment with colchicine, he became completely asymptomatic, drawing one's attention of calcium crystal-associated arthropathy as a cause of febrile systemic inflammatory disease particularly in elderly population.

摘要

关节内晶体形成和沉积是急性关节炎的一个重要且常见病因。该病可能伴有发热和全身症状。在本报告中,我们描述了一名70岁男性的病例,他突发大小关节均受累且严重影响功能的多关节炎,伴有发热、乏力和白细胞增多。经过广泛检查,关节X线检查显示存在软骨钙质沉着症。使用秋水仙碱治疗几天后,他完全无症状,这使人们注意到钙晶体相关关节病是发热性全身炎症性疾病的一个病因,尤其是在老年人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a4/6544428/abe76dd30ac5/omz030f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a4/6544428/819c754fdd86/omz030f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a4/6544428/abe76dd30ac5/omz030f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a4/6544428/819c754fdd86/omz030f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a4/6544428/abe76dd30ac5/omz030f2.jpg

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Front Med (Lausanne). 2020 Apr 30;7:166. doi: 10.3389/fmed.2020.00166. eCollection 2020.

本文引用的文献

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Update on calcium pyrophosphate deposition.焦磷酸钙沉积病的最新进展
Clin Exp Rheumatol. 2016 Jul-Aug;34(4 Suppl 98):32-8. Epub 2016 Jul 22.
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Nonpharmacologic and pharmacologic management of CPP crystal arthritis and BCP arthropathy and periarticular syndromes.CPP晶体关节炎、BCP关节病及关节周围综合征的非药物和药物治疗
Rheum Dis Clin North Am. 2014 May;40(2):343-56. doi: 10.1016/j.rdc.2014.01.010. Epub 2014 Feb 19.
3
Diagnosis and clinical manifestations of calcium pyrophosphate and basic calcium phosphate crystal deposition diseases.
焦磷酸钙和碱性磷酸钙晶体沉积病的诊断与临床表现
Rheum Dis Clin North Am. 2014 May;40(2):207-29. doi: 10.1016/j.rdc.2014.01.011. Epub 2014 Mar 4.
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Clinical implications of pathogenic calcium crystals.致病钙晶体的临床意义。
Curr Opin Rheumatol. 2014 Mar;26(2):192-6. doi: 10.1097/BOR.0000000000000038.
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Eighteen cases of crowned dens syndrome: Presentation and diagnosis.18例颅底凹陷综合征:临床表现与诊断
Neurochirurgie. 2013 Jun;59(3):115-20. doi: 10.1016/j.neuchi.2013.03.003. Epub 2013 Jun 24.
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Calcium pyrophosphate deposition disease: clinical manifestations.焦磷酸钙沉积病:临床表现
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The mechanisms of inflammation in gout and pseudogout (CPP-induced arthritis).痛风和假性痛风(焦磷酸钙诱导的关节炎)的炎症机制。
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European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis.欧洲抗风湿病联盟焦磷酸钙沉积症建议。第一部分:术语和诊断。
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