Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Barry University, Miami, Florida, USA.
Eur Eat Disord Rev. 2024 Mar;32(2):230-243. doi: 10.1002/erv.3038. Epub 2023 Oct 14.
This study examined the feasibility and preliminary effectiveness of a cognitive-behavioral, family-centered partial hospitalization program (PHP) for adolescents with anorexia nervosa (AN) and atypical AN (AAN), and described the outpatient services received following discharge. Participants (N = 31) completed anthropometric and self-report assessments at admission, discharge, and six and twelve months after discharge from the PHP. Descriptive statistics explored markers of feasibility. Paired samples t-tests evaluated changes in weight and eating disorder (ED) symptomatology from admission to discharge, admission to six-month follow-up, and admission to twelve-month follow-up. Descriptive statistics and effect sizes compared symptoms at each timepoint between participants with AN and AAN. Results indicated that we were successful at recruiting greater than 50% of adolescents approached for this study. We collected follow-up data from more than 70% of participants at discharge, but did not meet this retention benchmark at six-month and twelve-month follow-ups. The entire sample demonstrated significant improvements in weight and ED symptomatology from admission to discharge, and generally maintained these improvements at six- and twelve-month follow-up. While descriptive statistics suggested that participants with AN and AAN received similar outpatient services following discharge from the PHP, those with AN experienced greater improvement in self-reported ED symptomatology than those with AAN at six- and twelve-month follow-up. These findings provide preliminary support for the efficacy of PHPs in treating adolescents with AN and AAN. Further research with larger sample sizes should investigate whether adolescents with AAN experience poorer outcomes than those with AN following discharge from a PHP.
本研究考察了认知行为、以家庭为中心的青少年神经性厌食症（AN）和非典型 AN（AAN）部分住院治疗计划（PHP）的可行性和初步效果，并描述了出院后的门诊服务。参与者（N=31）在入院、出院以及出院后 6 个月和 12 个月时完成了人体测量和自我报告评估。描述性统计数据探讨了可行性指标。配对样本 t 检验评估了从入院到出院、从入院到 6 个月随访以及从入院到 12 个月随访期间体重和饮食障碍（ED）症状的变化。描述性统计和效应量比较了 AN 和 AAN 参与者在每个时间点的症状。结果表明，我们成功招募了超过 50%的研究对象。我们在出院时收集了超过 70%的参与者的随访数据，但在 6 个月和 12 个月的随访中没有达到这一保留基准。整个样本在入院到出院期间体重和 ED 症状显著改善，并且在 6 个月和 12 个月的随访中基本保持了这些改善。虽然描述性统计表明，出院后接受 PHP 治疗的 AN 和 AAN 参与者接受了类似的门诊服务，但在 6 个月和 12 个月的随访中，AN 患者的自我报告 ED 症状改善程度大于 AAN 患者。这些发现为 PHP 治疗 AN 和 AAN 青少年的疗效提供了初步支持。需要进一步研究更大样本量，以调查 AAN 患者在 PHP 出院后是否比 AN 患者的结局更差。
