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在血液透析期间使用局部氧疗治愈难愈合伤口。

Healing Tough Wounds Using Topical Oxygen Therapy During Hemodialysis Sessions.

作者信息

Segev Ronen

机构信息

Lecturer, Department of Nursing, Ruppin Academic Center, Emek-Hefer, Israel.

出版信息

Nephrol Nurs J. 2019 May-Jun;46(3):330-336.

PMID:31199100
Abstract

Topical oxygen therapy (TOT) is used widely in the treatment of difficult-to-heal arterial and venous ulcers in patients with peripheral vascular disease (PVD), diabetic ulcers, and lower extremity venous insufficiency. Successful TOT relies on supplying 100% oxygen at 1.04 atmospheres to the ulcered area. In principle, TOT allows a rapid proliferation of new epithelium over the ulcer. This article describes two case studies with successful wound healing as a result of using this clinical method during hemodialysis sessions.

摘要

局部氧疗(TOT)广泛应用于治疗外周血管疾病(PVD)患者的难愈合动静脉溃疡、糖尿病溃疡和下肢静脉功能不全。成功的局部氧疗依赖于在1.04个大气压下向溃疡区域供应100%的氧气。原则上,局部氧疗能使溃疡表面迅速形成新的上皮组织。本文介绍了两例在血液透析过程中使用这种临床方法实现伤口成功愈合的病例研究。

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1
Healing Tough Wounds Using Topical Oxygen Therapy During Hemodialysis Sessions.在血液透析期间使用局部氧疗治愈难愈合伤口。
Nephrol Nurs J. 2019 May-Jun;46(3):330-336.
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Topical oxygen therapy stimulates healing in difficult, chronic wounds: a tertiary centre experience.局部氧疗可促进难愈性慢性伤口的愈合:一家三级中心的经验。
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Adjunctive topical oxygen therapy for wound healing in patients with peripheral arterial disease.辅助性局部氧疗用于外周动脉疾病患者的伤口愈合
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Guidelines for the use of topical oxygen therapy in the treatment of hard-to-heal wounds based on a Delphi consensus.基于德尔菲共识的局部氧疗治疗难愈性伤口指南。
J Wound Care. 2022 Mar 1;31(Sup3):S20-S24. doi: 10.12968/jowc.2022.31.Sup3.S20.
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The efficacy of topical oxygen therapy for wound healing: A meta-analysis of randomized controlled trials and observational studies.局部氧疗促进伤口愈合的疗效:随机对照试验和观察性研究的荟萃分析。
Int Wound J. 2024 Jul;21(7):e14960. doi: 10.1111/iwj.14960.
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Poorly designed research does not help clarify the role of hyperbaric oxygen in the treatment of chronic diabetic foot ulcers.设计不佳的研究无助于阐明高压氧在慢性糖尿病足溃疡治疗中的作用。
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UHMS position statement: topical oxygen for chronic wounds.美国高压氧医学学会立场声明:慢性伤口的局部用氧
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Topical oxygen therapy promotes the healing of chronic diabetic foot ulcers: a pilot study.局部氧疗促进慢性糖尿病足溃疡愈合:一项初步研究。
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引用本文的文献

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Systematic review of the effects of topical oxygen therapy on wound healing.局部氧疗对伤口愈合影响的系统评价
JVS Vasc Insights. 2024;2. doi: 10.1016/j.jvsvi.2023.100051. Epub 2023 Dec 30.
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KADAM topical warm oxygen therapy device for diabetic foot ulcer-a novel approach.用于糖尿病足溃疡的KADAM局部温热氧疗装置——一种新方法。
J Diabetes Metab Disord. 2022 Dec 21;22(1):507-514. doi: 10.1007/s40200-022-01172-3. eCollection 2023 Jun.
3
Transient exposure to elevated glucose levels causes persistent changes in dermal microvascular endothelial cell responses to injury.
短暂暴露于高血糖水平会导致真皮微血管内皮细胞对损伤的反应发生持续变化。
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