Hutchinson Barry D, Shroff Girish S, Truong Mylene T, Ko Jane P
Department of Radiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY.
Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Semin Ultrasound CT MR. 2019 Jun;40(3):255-264. doi: 10.1053/j.sult.2018.11.009. Epub 2018 Nov 30.
Lung cancer remains the most common cause of cancer death in the United States of America and worldwide despite continued advances in lung cancer screening as well as surgical, medical, and radiation oncological treatments. Adenocarcinoma is the most common histological subtype of primary lung cancer and has recently been reorganized into a spectrum ranging from preinvasive lesions to invasive adenocarcinoma. An understanding of the pathology, diagnosis, and management of the spectrum of lung adenocarcinoma is more important than ever, considering the central role of the radiologist. The aim of this review is to describe the subtypes of the lung adenocarcinoma spectrum in terms of histological and imaging features, their pattern of growth on imaging, management, staging, and evolving knowledge of tumor genetics.
尽管肺癌筛查以及外科、内科和放射肿瘤学治疗不断取得进展，但肺癌仍然是美国和全球癌症死亡的最常见原因。腺癌是原发性肺癌最常见的组织学亚型，最近已被重新划分为一个范围，从浸润前病变到浸润性腺癌。考虑到放射科医生的核心作用，了解肺腺癌谱系的病理学、诊断和管理比以往任何时候都更加重要。本综述的目的是根据组织学和影像学特征、它们在影像学上的生长模式、管理、分期以及肿瘤遗传学的不断发展的知识，描述肺腺癌谱系的亚型。
