Cohen J G, Reymond E, Jankowski A, Brambilla E, Arbib F, Lantuejoul S, Ferretti G R
Clinique universitaire de radiologie et imagerie médicale (CURIM), CHU A.-Michallon, BP 217, 38043 Grenoble cedex 9, France; Université Grenoble-Alpes, 38000 Grenoble, France.
Clinique universitaire de radiologie et imagerie médicale (CURIM), CHU A.-Michallon, BP 217, 38043 Grenoble cedex 9, France.
Diagn Interv Imaging. 2016 Oct;97(10):955-963. doi: 10.1016/j.diii.2016.06.021. Epub 2016 Sep 14.
Adenocarcinoma is the most common histologic type of lung cancer. Recent lung adenocarcinoma classifications from the International Association for the Study of Lung cancer, the American Thoracic Society and the European Respiratory Society (IASLC/ETS/ERS, 2011) and World Health Organization (WHO, 2015) define a wide range of adenocarcinoma types and subtypes featuring different prognosis and management. This spectrum of lesions translates into various CT presentations and features, which generally show good correlation with histopathology, stressing the key role of the radiologist in the diagnosis and management of those patients. This review aims at helping radiologists to understand the basics of the up-to-date adenocarcinoma pathological classifications, radio-pathological correlations and how to use them in the clinical setting, as well as other imaging-related correlations (radiogenomics, quantitative analysis, PET-CT).
腺癌是肺癌最常见的组织学类型。国际肺癌研究协会、美国胸科学会和欧洲呼吸学会(IASLC/ETS/ERS,2011年)以及世界卫生组织(WHO,2015年)最近的肺癌腺癌分类定义了多种腺癌类型和亚型,它们具有不同的预后和治疗方法。这种病变谱转化为各种CT表现和特征,通常与组织病理学表现出良好的相关性,这突出了放射科医生在这些患者的诊断和治疗中的关键作用。本综述旨在帮助放射科医生了解最新腺癌病理分类的基础知识、放射病理相关性以及如何在临床环境中应用它们,以及其他与影像相关的相关性(放射基因组学、定量分析PET-CT)。