Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Department of Orthopaedics, Osaka University Graduate School of Medicine, Osaka, Japan.
Cartilage. 2021 Dec;13(1_suppl):31S-41S. doi: 10.1177/1947603519855767. Epub 2019 Jun 16.
The purpose of this systematic review is to determine (1) current reported treatment options for isolated tibial plateau (TP) cartilage lesions, (2) patient reported outcomes following various treatments, and (3) complication rate and survivorship following various treatments.
A literature search of PubMed, the Cochrane Library, and CINAHL was conducted adhering to PRISMA guidelines. Patients were included if they had TP cartilage lesions treated with surgery. Lesion characteristics, surgical procedure details, patient reported outcomes, complication, and failure rates were collected.
Thirteen studies yielded 205 knees with TP cartilage lesions treated surgically. Ages ranged from 12 to 77 years. Surgical techniques included 138 treated with osteochondral allograft transplantation (OCA), 37 treated with osteochondral autograft transfer system (OATS), 11 treated with microfracture, 11 treated with an osteochondral scaffold, and 8 treated with autologous chondrocyte implantation (ACI). The patient-reported outcome measures were heterogeneous, but all reported improvements with the notable exception of one study evaluating microfracture. The rate of complications ranged from 0% to 4.6%. Failure rate ranged from 22% to 46% for OCA and 0% to 16% for OATS. No failures were reported for the additional techniques.
Various surgical techniques have been utilized for the treatment of TP cartilage lesions. Patient-reported outcome measures were heterogeneous, but improvements were reported following all surgical treatments except for microfracture, which resulted in decreased scores at mid-term follow-up. The complication rate was low for all techniques described. However, the failure rate was higher following unicondylar OCA for salvage treatment of posttraumatic deformities.
本系统评价旨在确定:(1) 孤立性胫骨平台(TP)软骨损伤的当前报告治疗选择;(2) 各种治疗方法后的患者报告结局;以及 (3) 各种治疗方法后的并发症发生率和存活率。
根据 PRISMA 指南,对 PubMed、Cochrane 图书馆和 CINAHL 进行文献检索。纳入接受手术治疗的 TP 软骨损伤患者。收集了病变特征、手术过程细节、患者报告的结局、并发症和失败率。
13 项研究共纳入 205 例接受手术治疗的 TP 软骨损伤患者。年龄从 12 岁到 77 岁不等。手术技术包括 138 例接受骨软骨同种异体移植(OCA)治疗、37 例接受骨软骨自体移植系统(OATS)治疗、11 例接受微骨折治疗、11 例接受骨软骨支架治疗和 8 例接受自体软骨细胞移植(ACI)治疗。患者报告的结局测量指标存在异质性,但所有研究均报告有所改善,只有一项评估微骨折的研究除外。并发症发生率从 0%到 4.6%不等。OCA 的失败率从 22%到 46%不等,OATS 的失败率从 0%到 16%不等。其他技术未报告失败。
各种手术技术已被用于治疗 TP 软骨损伤。患者报告的结局测量指标存在异质性,但除微骨折外,所有手术治疗均报告有所改善,微骨折在中期随访时导致评分降低。所有描述的技术的并发症发生率均较低。然而,对于创伤后畸形的挽救性治疗,单髁 OCA 的失败率更高。