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膝关节软骨修复技术的现代理念。

Current concepts of articular cartilage restoration techniques in the knee.

机构信息

Department of Orthopedic Surgery and the Sports Medicine Center, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

出版信息

Sports Health. 2014 May;6(3):265-73. doi: 10.1177/1941738113508917.

DOI:10.1177/1941738113508917
PMID:24790697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4000472/
Abstract

CONTEXT

Articular cartilage injuries are common in patients presenting to surgeons with primary complaints of knee pain or mechanical symptoms. Treatment options include comprehensive nonoperative management, palliative surgery, joint preservation operations, and arthroplasty.

EVIDENCE ACQUISITION

A MEDLINE search on articular cartilage restoration techniques of the knee was conducted to identify outcome studies published from 1993 to 2013. Special emphasis was given to Level 1 and 2 published studies.

STUDY DESIGN

Clinical review.

LEVEL OF EVIDENCE

Level 3.

RESULTS

CURRENT SURGICAL OPTIONS WITH DOCUMENTED OUTCOMES IN TREATING CHONDRAL INJURIES IN THE KNEE INCLUDE THE FOLLOWING: microfracture, osteochondral autograft transfer, osteochondral allograft transplant, and autologous chondrocyte transplantation. Generally, results are favorable regarding patient satisfaction and return to sport when proper treatment algorithms and surgical techniques are followed, with 52% to 96% of patients demonstrating good to excellent clinical outcomes and 66% to 91% returning to sport at preinjury levels.

CONCLUSION

Clinical, functional, and radiographic outcomes may be improved in the majority of patients with articular cartilage restoration surgery; however, some patients may not fully return to their preinjury activity levels postoperatively. In active and athletic patient populations, biological techniques that restore the articular surface may be options that provide symptom relief and return patients to their prior levels of function.

摘要

背景

关节软骨损伤在因膝关节疼痛或机械性症状就诊的患者中较为常见。治疗选择包括全面的非手术治疗、姑息性手术、关节保留手术和关节置换术。

证据获取

对膝关节关节软骨修复技术进行了 MEDLINE 检索,以确定 1993 年至 2013 年发表的疗效研究。特别强调了发表的 1 级和 2 级研究。

研究设计

临床综述。

证据水平

3 级。

结果

目前在膝关节治疗软骨损伤方面具有明确疗效的手术选择包括以下几种:微骨折术、骨软骨自体移植、骨软骨异体移植和自体软骨细胞移植。一般来说,当遵循适当的治疗方案和手术技术时,患者满意度和重返运动的结果是良好的,52%至 96%的患者表现出良好到优秀的临床疗效,66%至 91%的患者恢复到术前运动水平。

结论

大多数接受关节软骨修复手术的患者的临床、功能和影像学结果可能会得到改善;然而,一些患者术后可能无法完全恢复到受伤前的活动水平。在活跃和运动的患者群体中,恢复关节表面的生物技术可能是提供症状缓解并使患者恢复到之前功能水平的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/e23383567a28/10.1177_1941738113508917-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/ea7f18e1d580/10.1177_1941738113508917-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/9375b2c11bc6/10.1177_1941738113508917-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/3fe8b8f5f7c2/10.1177_1941738113508917-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/364ee608a472/10.1177_1941738113508917-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/b8927518365c/10.1177_1941738113508917-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/5a0a1085d944/10.1177_1941738113508917-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/e23383567a28/10.1177_1941738113508917-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/ea7f18e1d580/10.1177_1941738113508917-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/9375b2c11bc6/10.1177_1941738113508917-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/3fe8b8f5f7c2/10.1177_1941738113508917-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/364ee608a472/10.1177_1941738113508917-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/b8927518365c/10.1177_1941738113508917-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/5a0a1085d944/10.1177_1941738113508917-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d53/4000472/e23383567a28/10.1177_1941738113508917-fig7.jpg

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