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皮肤之下:一例罕见的坏血病相关性巨幼细胞贫血病例

Behind the Skin: A Rare Case of Scurvy-Associated Megaloblastic Anemia.

作者信息

Alhatem Albert, Cai Donghong

机构信息

Department of Pathology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.

Department of Pathology and Laboratory Medicine, Veterans Affairs New Jersey Health Care System, East Orange, NJ, USA.

出版信息

Clin Med Insights Case Rep. 2019 May 10;12:1179547619849036. doi: 10.1177/1179547619849036. eCollection 2019.

Abstract

Scurvy, caused by vitamin C deficiency, is very rare nowadays in the developed world. Scattered cases are found in people with unusual eating habits, alcoholism, intestinal malabsorption, mental disorders, or elderly living alone. Because of its rarity, clinical presentations of scurvy, especially anemia and bleeding, are no longer well appreciated, and consequently extensive evaluation is commonly launched to pursue scurvy mimics, such as deep vein thrombosis, vasculitis, systemic coagulation disorders, and myelodysplasia. Herein, we describe the clinical manifestations and lab findings in a scurvy patient to raise awareness of this uncommon disease.

摘要

坏血病由维生素C缺乏引起,如今在发达国家极为罕见。在饮食习惯异常、酗酒、肠道吸收不良、精神障碍患者或独居老人中发现有散发病例。由于其罕见性,坏血病的临床表现,尤其是贫血和出血,已不再被充分认识,因此通常会进行广泛评估以排查坏血病的模仿疾病,如深静脉血栓形成、血管炎、全身性凝血障碍和骨髓增生异常综合征。在此,我们描述了一名坏血病患者的临床表现和实验室检查结果,以提高对这种罕见疾病的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be6/6537289/78ad20fbaa53/10.1177_1179547619849036-fig1.jpg

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