Departamento de Atención a la Salud, Universidad Autónoma Metropolitana-Xochimilco, Ciudad de Mexico, Mexico.
Departamento de Investigación Básica, Instituto Nacional de Geriatría, Ciudad de Mexico, Mexico.
Nutr Diet. 2020 Nov;77(5):515-522. doi: 10.1111/1747-0080.12551. Epub 2019 Jun 17.
To evaluate the prevalence of sarcopenia and its association with nutritional status and type 2 diabetes mellitus (T2DM) in older women living in a nursing home.
This cross-sectional study assessed nutritional status using the Mini Nutritional Assessment (MNA). Sarcopenia was defined according to the European Working Group on Sarcopenia in Older People; hand grip strength and physical performance were determined by dynamometry and gait speed, respectively. Muscle mass was assessed using calf circumference.
The mean age of the 114 participants was 84.1 ± 7.0 years. The prevalence of sarcopenia and T2DM was 30.7% and 10.5%, respectively. The majority (66.7%) had a normal nutritional status, 29.8% were at risk of malnutrition, and 3.5% were undernourished. The prevalence of sarcopenia in participants at risk of malnutrition and those who were undernourished was higher compared with participants with a normal NS (P < 0.0001). A statistically significant difference was observed in the Barthel Index (BI) between women with and without sarcopenia (P = 0.048). The multivariate logistic regression model, adjusted by age (p = 0.007) showed an association between sarcopenia and nutritional status. Women with a poor nutritional status were more likely to have sarcopenia (OR 4.97, P = 0.003) whilst those with T2DM showed a higher probability of sarcopenia (OR 5.52, P = 0.019) than women without T2DM.
Sarcopenia was highly prevalent in women with a poor nutritional status and T2DM. It is necessary to implement intervention programs to reduce adverse outcomes.
评估养老院中老年女性肌少症的患病率及其与营养状况和 2 型糖尿病（T2DM）的关系。
本横断面研究采用 Mini Nutritional Assessment（MNA）评估营养状况。肌少症根据欧洲老年人肌少症工作组的定义进行定义；握力和身体表现分别通过测力和步速来确定。肌肉质量通过小腿围评估。
114 名参与者的平均年龄为 84.1±7.0 岁。肌少症和 T2DM 的患病率分别为 30.7%和 10.5%。大多数（66.7%）有正常的营养状况，29.8%有营养不良风险，3.5%有营养不良。与有正常 NS 的参与者相比，处于营养不良风险和营养不良的参与者中肌少症的患病率更高（P<0.0001）。有肌少症和无肌少症的女性之间 Barthel 指数（BI）存在统计学差异（P=0.048）。多元逻辑回归模型，通过年龄调整（p=0.007），显示肌少症与营养状况之间存在关联。营养状况差的女性更有可能患有肌少症（OR 4.97，P=0.003），而患有 T2DM 的女性比没有 T2DM 的女性更有可能患有肌少症（OR 5.52，P=0.019）。
营养不良和 T2DM 的老年女性肌少症患病率较高。有必要实施干预计划以减少不良后果。
