1 Iowa State University, Ames, IA, USA.
Neurorehabil Neural Repair. 2019 Aug;33(8):595-601. doi: 10.1177/1545968319856893. Epub 2019 Jun 18.
Sedentary behavior is a growing public health concern and may have particular relevance for the Parkinson disease (PD) population. However, the influence of sedentary time on factors associated with quality of life (QOL) in PD is unknown. The primary purpose of this study was to examine relationships between sedentary behaviors and markers of PD-specific QOL. A secondary purpose was to examine relationships between physical activity behaviors and QOL. We assessed sedentary and active behaviors using objective and interview measures and examined relationships between these behaviors and a measure of PD-specific QOL in individuals with PD. Results demonstrated that sedentary time was significantly related to several aspects of QOL, including perceived deficits in the domains of mobility, cognitive processing, and communication. Additionally, results showed that time spent watching television was more strongly associated with lower levels of QOL than other more engaging sedentary activities. For physical activity, relationships between objective measures and QOL were weaker and only significantly associated with mobility. Time spent doing housework was associated with lower levels of QOL, whereas time spent in recreational activity was associated with lower levels of discomfort. These results suggest that targeting decreases in sedentary behaviors (eg, reducing time spent watching television, breaking up prolonged bouts of sedentary time) may be effective for improving QOL in individuals with PD.
久坐行为是一个日益严重的公共卫生问题，可能与帕金森病（PD）人群特别相关。然而，久坐时间对与 PD 患者生活质量（QOL）相关因素的影响尚不清楚。本研究的主要目的是研究久坐行为与 PD 特定 QOL 标志物之间的关系。次要目的是研究身体活动行为与 QOL 之间的关系。我们使用客观和访谈测量来评估久坐和活跃行为，并研究这些行为与 PD 患者 PD 特定 QOL 测量之间的关系。结果表明，久坐时间与 QOL 的几个方面显著相关，包括在移动性、认知处理和沟通领域感知到的缺陷。此外，结果表明，看电视时间与较低的 QOL 水平比其他更具吸引力的久坐活动更密切相关。对于身体活动，客观测量与 QOL 之间的关系较弱，仅与移动性显著相关。做家务的时间与较低的 QOL 水平相关，而娱乐活动的时间与较低的不适水平相关。这些结果表明，减少久坐行为（例如，减少看电视时间，打破长时间久坐时间）可能对改善 PD 患者的 QOL 有效。
