Michałkiewicz J
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):801-5.
The investigation has been carried out on 30 patients with rheumatoid arthritis. Rosettes (E, EA, EAC) technique and immunofluorescence test were used to detect the surface markers of lymphocytes. Cytotoxic activity of T and K cells in vitro was established. It has been proved that cells occurred to a larger extend in synovial fluid than in the peripheral blood. B cells and lymphocytes with Fc receptors were only a few in synovial fluid. The percentage ofFc receptors bearing cells was higher in the peripheral blood of patients with rheumatoid arthritis than that in peripheral blood of the control group. Cytotoxic activity of K-cell was low in synovial fluid. PHA-cell mediated cytotoxicity was low in peripheral blood as well as in synovial fluid of patients with rheumatoid arthritis.
对30例类风湿性关节炎患者进行了调查。采用玫瑰花结（E、EA、EAC）技术和免疫荧光试验检测淋巴细胞的表面标志物。建立了T细胞和K细胞的体外细胞毒性活性。已证明细胞在滑液中出现的程度比在外周血中更大。滑液中B细胞和具有Fc受体的淋巴细胞很少。类风湿性关节炎患者外周血中带有Fc受体的细胞百分比高于对照组外周血。滑液中K细胞的细胞毒性活性较低。类风湿性关节炎患者外周血和滑液中PHA细胞介导的细胞毒性均较低。
