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在接受胸腔镜肺癌肺叶切除术的患者中,使用电动和组织特异性内镜吻合器的临床和经济效益。

Clinical and economic benefits associated with the use of powered and tissue-specific endoscopic staplers among the patients undergoing thoracoscopic lobectomy for lung cancer.

机构信息

Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

J Med Econ. 2019 Dec;22(12):1274-1280. doi: 10.1080/13696998.2019.1634081. Epub 2019 Jul 4.

Abstract

Thoracoscopic lobectomy for lung cancer is a complex procedure where endoscopic staplers play a critical role in transecting the lung parenchyme, vasculature, and bronchus. This retrospective study was performed to investigate the economic benefits of powered and tissue-specific endoscopic staplers such as gripping surface technology (GST) and powered vascular stapler (PVS) compared to standard staplers. Two hundred and seventy-five patients who received a thoracoscopic lobectomy between 2008 and 2016 were included. Group 1 ( 117) consisted of patients who received the operation with manual endoscopic staplers, whereas Group 2 ( 158) consisted of patients who received the operation with GST and PVS. Patient demographics and clinical characteristics were comparable, except smoking history, pulmonary function, and pleural adhesion. All patients received the operation successfully without mortalities and broncho-pleural fistula. Operation time and blood loss were higher in Group 1. Pleurodesis was performed less in Group 2 than in Group 1 (18.0% vs 3.8%,  < 0.0001). Group 2 had statistically significant lower adjusted hospital costs (Korean Won, 14,610,162 ± 4,386,628 vs 12,876,111 ± 5,010,878,  < 0.0001), lower adjusted hemostasis related costs (198,996 ± 110,253 vs 175,291 ± 191,003,  = 0.0101); lower cartridge related adjusted costs (1,105,091 ± 489,838 vs 839,011 ± 307,894,  < 0.0001) compared to Group 1. As well, Group 2 showed ∼12% lower adjusted total hospital costs compared to Group 1. Multivariable analysis revealed that Group 1 was related to increased hospital costs. This study showed that thoracoscopic lobectomy with powered and tissue-specific endoscopic staplers were associated with better clinical outcomes and reduced adjusted hospital costs when compared in Korean real-world settings.

摘要

胸腔镜肺癌肺叶切除术是一项复杂的手术,腔内吻合器在切断肺实质、血管和支气管方面起着关键作用。本回顾性研究旨在探讨夹持面技术(GST)和电动血管吻合器(PVS)等动力和组织特异性腔内吻合器与标准吻合器相比的经济效益。纳入 2008 年至 2016 年间接受胸腔镜肺叶切除术的 275 例患者。第 1 组(117 例)患者接受手动腔内吻合器手术,第 2 组(158 例)患者接受 GST 和 PVS 手术。两组患者的人口统计学和临床特征相似,但吸烟史、肺功能和胸膜粘连不同。所有患者均成功接受手术,无死亡和支气管胸膜瘘发生。第 1 组的手术时间和出血量较高。与第 1 组相比,第 2 组的胸膜固定术较少(18.0%对 3.8%, < 0.0001)。第 2 组的调整后住院费用(韩元,14610162 ± 4386628 对 12876111 ± 5010878, < 0.0001)、调整后止血相关费用(198996 ± 110253 对 175291 ± 191003, = 0.0101)、调整后管腔吻合器相关费用(1105091 ± 489838 对 839011 ± 307894, < 0.0001)均明显低于第 1 组。同样,第 2 组与第 1 组相比,调整后总住院费用降低约 12%。多变量分析显示,第 1 组与住院费用增加有关。本研究表明,在韩国的真实环境中,与使用手动腔内吻合器相比,使用电动和组织特异性腔内吻合器进行胸腔镜肺叶切除术可获得更好的临床效果,并降低调整后的住院费用。

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