Lima-Junior Edmar Maciel, de Moraes Filho Manoel Odorico, Costa Bruno Almeida, Fechine Francisco Vagnaldo, de Moraes Maria Elisabete Amaral, Silva-Junior Francisco Raimundo, Soares Maria Flaviane Araújo do Nascimento, Rocha Marina Becker Sales, Leontsinis Cybele Maria Philopimin
Burn Treatment Center, Dr. José Frota Institute, 60025-061, Fortaleza, CE, Brazil.
Clinical Pharmacology Unit, Drug Research and Development Center, 60430-275, Federal University of Ceará (UFC), Fortaleza, CE, Brazil.
J Surg Case Rep. 2019 Jun 14;2019(6):rjz181. doi: 10.1093/jscr/rjz181. eCollection 2019 Jun.
Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center after a thermal injury caused by contact with flames from a gunpowder explosion. Superficial partial thickness burns were present in his right upper limb and deep partial thickness burns were present in his left upper limb. Tilapia skin was applied to the lesions, leading to complete reepithelialization within 12 and 17 days of treatment, respectively. No dressing changes were needed and no side effects were observed. Tilapia skin carries the promise of an innovative, easy-to-apply and highly available product that can become the first nationally studied animal skin registered by the National Sanitary Surveillance Agency for use in the treatment of burns.
罗非鱼皮具有非感染性微生物群、大量的I型胶原蛋白,且其形态结构与人类皮肤相似,因此有人建议将其作为治疗烧伤创面的潜在异种移植物。一名23岁无合并症的男性患者,在接触火药爆炸产生的火焰导致热损伤后,来到我们的烧伤治疗中心。其右上肢为浅Ⅱ度烧伤,左上肢为深Ⅱ度烧伤。将罗非鱼皮应用于创面,分别在治疗后12天和17天实现了完全上皮化。无需更换敷料,也未观察到副作用。罗非鱼皮有望成为一种创新的、易于应用且易于获取的产品,成为首个经国家卫生监督机构注册用于烧伤治疗的全国性研究动物皮肤。