Department of Pediatric Dentistry, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Oral and Maxillofacial Radiology, School of Dentistry, Kermanshah University of Medical Sciences, Building No. 1, Shahid Beheshti Boulevard, Kermanshah, 6715847141, Iran.
BMC Oral Health. 2019 Jun 19;19(1):121. doi: 10.1186/s12903-019-0813-6.
This study aimed to assess the efficacy of a 980-nm diode and 10.6-μm CO laser accompanied by tricalcium phosphate-5% sodium fluoride (fTCP) and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) for the remineralization of primary teeth.
In total, 117 extracted primary anterior teeth were randomly divided into eight experimental and one control group: (I) control (polished enamel), (II) fTCP varnish, (III) fTCP + diode laser, (IV) fTCP + CO laser, (V) CPP-ACP, (VI) CPP-ACP + diode laser, (VII) CPP-ACP + CO laser, (VIII) diode laser, and (IX) CO laser. The microhardness of 12 samples in each group and the enamel porosity of one sample in each group were assessed before and after demineralization and 28 days after remineralization. Data were analysed using two-way ANOVA.
Significant differences existed in microhardness (P = 0.004) and percentage of remineralization (P < 0.001) after remineralization among the material groups such that the highest mean was noted in the CPP-ACP group. No significant difference was noted in microhardness (P = 0.052) or percentage of remineralization (P = 0.981) after remineralization among the laser groups. In all groups, porosities increased after demineralization and slightly decreased after remineralization; the greatest reduction in porosity of the material groups was noted in the fTCP group, and the CO group among the laser groups. The interaction effect of materials and lasers was not significant (P > 0.05).
The highest microhardness was achieved after remineralization with CPP-ACP. The efficacy of the diode and CO lasers was the same. No synergistic effect was found between materials and lasers.
This is not a human subject research.
本研究旨在评估 980nm 二极管和 10.6μm CO 激光联合磷酸三钙-5%氟化钠（fTCP）和酪蛋白磷酸肽无定形磷酸钙（CPP-ACP）对乳牙再矿化的疗效。
共 117 颗离体前乳牙随机分为八组实验组和一组对照组：（I）对照组（抛光釉质），（II）fTCP 涂料，（III）fTCP+二极管激光，（IV）fTCP+CO 激光，（V）CPP-ACP，（VI）CPP-ACP+二极管激光，（VII）CPP-ACP+CO 激光，（VIII）二极管激光和（IX）CO 激光。每组 12 个样本的显微硬度和每组 1 个样本的釉质孔隙率在脱矿化前后和再矿化 28 天后进行评估。数据采用双因素方差分析。
再矿化后材料组的显微硬度（P=0.004）和再矿化百分率（P<0.001）存在显著差异，CPP-ACP 组的平均水平最高。激光组的显微硬度（P=0.052）或再矿化百分率（P=0.981）无显著差异。所有组的脱矿化后孔隙率增加，再矿化后略有减少；材料组中 fTCP 组的孔隙率降低最大，激光组中 CO 组的孔隙率降低最大。材料和激光的交互作用不显著（P>0.05）。
CPP-ACP 再矿化后硬度最高。二极管激光和 CO 激光的疗效相同。材料和激光之间没有协同作用。
这不是人体研究。
