Suppr超能文献

用于评估持续性姿势感知性头晕(PPPD)严重程度的验证性问卷:新潟 PPPD 问卷(NPQ)。

A Validated Questionnaire to Assess the Severity of Persistent Postural-Perceptual Dizziness (PPPD): The Niigata PPPD Questionnaire (NPQ).

机构信息

Department of Otolaryngology, Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

出版信息

Otol Neurotol. 2019 Aug;40(7):e747-e752. doi: 10.1097/MAO.0000000000002325.

Abstract

OBJECTIVE

To establish a questionnaire to diagnose and assess the severity of persistent postural-perceptual dizziness (PPPD).

STUDY DESIGN

Retrospective chart review.

SETTING

Tertiary referral center.

PATIENTS

Fifty PPPD patients and 50 consecutive control patients with other vestibular disorders.

INTERVENTIONS

Patients answered questions on three exacerbating factors of PPPD (upright posture/walking, movement, and visual stimulation), and each factor was evaluated using four questions scoring the severity from 0 (none) to 6 (unbearable). Somatic and psychological distress was evaluated by the Visual Analog Scale (VAS) and the Hospital Anxiety and Depression Scale (HADS), respectively.

MAIN OUTCOME MEASURES

The questionnaire's reliability was tested by Cronbach's alpha, and it was validated by examining the differences in the questionnaire's scores between PPPD patients and controls. The area under the curve (AUC) of the receiver operating characteristic curve for each factor was calculated.

RESULTS

Cronbach's alpha coefficient was >0.8 for all factors, except the movement factor. There were no significant differences in the VAS and HADS scores between the two groups. However, the combined and individual questionnaire scores for each factor were higher in PPPD patients than in controls, indicating the questionnaire's high validity. The AUC was widest for the visual stimulation factor (0.830), and a score of 9 (full score 24) had the best sensitivity (82%) and specificity (74%) for discriminating PPPD patients from controls.

CONCLUSIONS

We developed a questionnaire that exhibited high reliability and validity in evaluating PPPD severity. The visual stimulation factor may be the most characteristic among the three exacerbating factors.

摘要

目的

建立一种用于诊断和评估持续性姿势感知性头晕(PPPD)严重程度的问卷。

研究设计

回顾性图表审查。

设置

三级转诊中心。

患者

50 例 PPPD 患者和 50 例连续的其他前庭障碍对照组患者。

干预措施

患者回答三个 PPPD 加重因素(直立姿势/行走、运动和视觉刺激)的问题,每个因素均采用 4 个问题进行评估,评分范围为 0(无)至 6(无法忍受)。躯体和心理困扰分别用视觉模拟量表(VAS)和医院焦虑抑郁量表(HADS)评估。

主要观察指标

用 Cronbach's alpha 检验问卷的可靠性,通过比较 PPPD 患者和对照组之间问卷评分的差异来验证其有效性。计算每个因素的受试者工作特征曲线下面积(AUC)。

结果

除运动因素外,所有因素的 Cronbach's alpha 系数均>0.8。两组间 VAS 和 HADS 评分无显著差异。然而,PPP 患者的组合和个体问卷评分在各因素中均高于对照组,表明问卷具有较高的有效性。视觉刺激因素的 AUC 最宽(0.830),评分 9 分(满分 24 分)对区分 PPPD 患者和对照组具有最佳的敏感性(82%)和特异性(74%)。

结论

我们开发了一种具有较高可靠性和有效性的问卷,用于评估 PPPD 的严重程度。在三个加重因素中,视觉刺激因素可能最具特征性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd0b/6641087/9fb526f650aa/mao-40-e747-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验