Staab Jeffrey P, Eckhardt-Henn Annegret, Horii Arata, Jacob Rolf, Strupp Michael, Brandt Thomas, Bronstein Adolfo
Departments of Psychiatry and Psychology and Otorhinolaryngology - Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA.
Department of Psychosomatic Medicine, Klinikum Stuttgart, Stuttgart, Germany.
J Vestib Res. 2017;27(4):191-208. doi: 10.3233/VES-170622.
This paper presents diagnostic criteria for persistent postural-perceptual dizziness (PPPD) to be included in the International Classification of Vestibular Disorders (ICVD). The term PPPD is new, but the disorder is not. Its diagnostic criteria were derived by expert consensus from an exhaustive review of 30 years of research on phobic postural vertigo, space-motion discomfort, visual vertigo, and chronic subjective dizziness. PPPD manifests with one or more symptoms of dizziness, unsteadiness, or non-spinning vertigo that are present on most days for three months or more and are exacerbated by upright posture, active or passive movement, and exposure to moving or complex visual stimuli. PPPD may be precipitated by conditions that disrupt balance or cause vertigo, unsteadiness, or dizziness, including peripheral or central vestibular disorders, other medical illnesses, or psychological distress. PPPD may be present alone or co-exist with other conditions. Possible subtypes await future identification and validation. The pathophysiologic processes underlying PPPD are not fully known. Emerging research suggests that it may arise from functional changes in postural control mechanisms, multi-sensory information processing, or cortical integration of spatial orientation and threat assessment. Thus, PPPD is classified as a chronic functional vestibular disorder. It is not a structural or psychiatric condition.
本文提出了持续性姿势-感知性头晕(PPPD)的诊断标准,该标准将被纳入《国际前庭疾病分类》(ICVD)。PPPD这个术语是新的,但这种疾病并非新出现的。其诊断标准是通过专家共识得出的,该共识基于对30年来关于恐惧性姿势性眩晕、空间-运动不适、视觉性眩晕和慢性主观性头晕的研究进行的详尽回顾。PPPD表现为一种或多种头晕、不稳或非旋转性眩晕症状,这些症状在大多数日子里持续三个月或更长时间,并且在直立姿势、主动或被动运动以及暴露于移动或复杂视觉刺激时会加重。PPPD可能由破坏平衡或导致眩晕、不稳或头晕的情况引发,包括外周或中枢前庭疾病、其他内科疾病或心理困扰。PPPD可能单独存在或与其他疾病共存。可能的亚型有待未来识别和验证。PPPD背后的病理生理过程尚不完全清楚。新出现的研究表明,它可能源于姿势控制机制、多感觉信息处理或空间定向与威胁评估的皮层整合方面的功能变化。因此,PPPD被归类为慢性功能性前庭疾病。它不是结构性疾病或精神疾病。