Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA
Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA.
Diabetes Care. 2019 Oct;42(10):1895-1902. doi: 10.2337/dc19-0707. Epub 2019 Jun 20.
We examined young adults with and young adults without diabetes by using demographic data and cardiometabolic risk profiles and compared the risk profiles of younger versus older (aged ≥45 years) adults with diabetes.
Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007-2016. Diabetes was defined by self-report of health care provider diagnosis or by A1C levels of 6.5% or higher among those without a self-reported diagnosis. The cardiometabolic risk profile included adiposity, blood pressure, serum lipids, healthy eating, physical activity (PA), and exposure to tobacco smoke. Adjusted difference in difference was calculated as the difference among younger adults with and younger adults without diabetes minus the difference among older adults with and older adults without diabetes.
Adults with diabetes in both age-groups had higher levels of adiposity, hypertension, and cholesterol and lower levels of healthy eating and leisure-time PA. However, the differences in high cholesterol and adiposity by diabetes status were greater among young adults compared with older adults after adjustment for demographics and health insurance status. Elevated lipids were 9.6 percentage points higher (95% CI 4.6, 14.5) and obesity was 37.3 percentage points higher (95% CI 31.8, 42.7) among young adults with diabetes compared with those without diabetes than among older adults with diabetes compared with those without diabetes.
Young adults with diabetes have high rates of cardiometabolic risk factors, which can lead to an increased disease prevalence and mortality rate among these individuals as they age.
我们通过人口统计学数据和心血管代谢风险特征检查了患有糖尿病的年轻成年人和无糖尿病的年轻成年人,并比较了年轻(年龄≥45 岁)与老年(年龄≥45 岁)糖尿病患者的风险特征。
数据来自 2007-2016 年全国健康和营养调查(NHANES)。糖尿病的定义是通过医疗保健提供者的诊断报告或未经诊断报告但 A1C 水平为 6.5%或更高来确定的。心血管代谢风险特征包括肥胖、血压、血清脂质、健康饮食、体力活动(PA)和接触烟草烟雾。调整后的差异差异计算为有糖尿病的年轻成年人和无糖尿病的年轻成年人之间的差异减去有糖尿病的老年成年人和无糖尿病的老年成年人之间的差异。
两个年龄组的糖尿病患者的肥胖、高血压和胆固醇水平更高,健康饮食和休闲时间 PA 水平更低。然而,在调整人口统计学和健康保险状况后,糖尿病患者的高胆固醇和肥胖差异在年轻成年人中比老年成年人更大。与无糖尿病的年轻成年人相比,有糖尿病的年轻成年人的血脂升高 9.6 个百分点(95%CI 4.6,14.5),肥胖率升高 37.3 个百分点(95%CI 31.8,42.7)。与无糖尿病的老年成年人相比,有糖尿病的老年成年人的血脂升高 5.0 个百分点(95%CI 1.5,8.5),肥胖率升高 16.1 个百分点(95%CI 8.5,23.6)。
年轻的糖尿病患者有很高的心血管代谢危险因素发生率,这会导致这些人随着年龄的增长,疾病患病率和死亡率增加。