Department of Neurology, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore 560029, India.
Department of Neurology, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore 560029, India.
J Neurol Sci. 2019 Aug 15;403:67-74. doi: 10.1016/j.jns.2019.06.009. Epub 2019 Jun 12.
Optical coherence tomography (OCT) has been evaluated as a tool to assess retinal changes in various neurodegenerative disorders. Parkinson's disease (PD), is a neurodegenerative disorder wherein dopaminergic deficiency results in some of the symptoms. As retina also has high concentration of dopamine, it would be of interest for both the clinician as well as the basic scientist to know if there is a correlation between the clinical features and the retinal changes. The objective of this review is to critically evaluate the literature and study the utility of OCT as a tool to evaluate retinal changes in PD.
光学相干断层扫描(OCT)已被评估为一种用于评估各种神经退行性疾病中视网膜变化的工具。帕金森病(PD)是一种神经退行性疾病,其中多巴胺能缺乏导致了一些症状。由于视网膜也具有高浓度的多巴胺,因此对于临床医生和基础科学家来说,了解临床特征与视网膜变化之间是否存在相关性都很有意义。本综述的目的是批判性地评估文献,并研究 OCT 作为评估 PD 中视网膜变化的工具的效用。