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罕见病例:孤立性脊柱骨软骨瘤恶变成为复发性转移性软骨肉瘤。

Rare case of malignant transformation of a solitary spinal osteochondroma into recurrent metastatic chondrosarcoma.

机构信息

Department of Neurosurgery, The Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia.

Department of Neurosurgery, The Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia.

出版信息

J Clin Neurosci. 2019 Sep;67:280-288. doi: 10.1016/j.jocn.2019.05.045. Epub 2019 Jun 19.

Abstract

Osteochondroma or osteocartilaginous exostosis is a commonly occurring primary tumor of the bone. Solitary spinal osteochondromas are, however, very rare, seen in only in 1-4% of all known cases and only few symptomatic cases have been reported in the literature so far. Further, while recurrence and malignant transformation are known to occur in osteochondroma, this is rare in the spine. We would like to report one such a case of an unusual presentation of recurrent, metastatic spinal chondrosarcoma in a patient with previous history of solitary cervical osteochondroma.

摘要

骨软骨瘤或骨软骨外生骨疣是一种常见的骨原发性肿瘤。然而,单发的脊柱骨软骨瘤非常罕见,仅占所有已知病例的 1-4%,且迄今为止文献中仅报道了少数有症状的病例。此外,虽然骨软骨瘤已知会复发和恶变,但在脊柱中这种情况较为罕见。我们报告一例不常见的复发性、转移性脊柱软骨肉瘤病例,该患者既往有单发颈椎骨软骨瘤病史。

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