Bouali Sofiene, Bouhoula Asma, Maatar Nidhal, Abderrahmen Khansa, Boubaker Adnen, Kallel Jalel, Jemel Hafedh
Department of Neurosurgery, National Institute of Neurology, Tunis, Tunisia.
Department of Neurosurgery, National Institute of Neurology, Tunis, Tunisia.
World Neurosurg. 2016 Aug;92:588.e1-588.e5. doi: 10.1016/j.wneu.2016.04.105. Epub 2016 May 4.
Chondrosarcoma is a rare malignant tumor of bone. This family of tumors can be primary malignant tumors or a secondary malignant transformation of an underlying benign cartilage tumor. Secondary chondrosarcoma arising from a benign solitary costal osteochondroma is extremely rare. Data show that the reported incidence of costal osteochondroma is very low and they are usually found in the anterior region at the costochondral junction. To our knowledge, however, there have been no previous reports, in English literature, describing osteochondroma malignant transformation located in the thoracic costovertebral junction.
We report the case of a man with chondrosarcoma arising from the malignant degeneration of an osteochondroma at the right first thoracic costovertebral junction with neural foraminal extension and compressing the spinal cord.
Although it is rare in solitary osteochondromas of rib, malignant transformation must always be considered.
软骨肉瘤是一种罕见的骨恶性肿瘤。这类肿瘤可以是原发性恶性肿瘤，也可以是潜在良性软骨肿瘤的继发性恶性转变。起源于良性孤立性肋骨骨软骨瘤的继发性软骨肉瘤极为罕见。数据显示，报道的肋骨骨软骨瘤发病率非常低，且通常位于肋软骨交界处的前部区域。然而，据我们所知，英文文献中此前尚无描述位于胸肋椎关节处的骨软骨瘤恶变的报道。
我们报告一例男性患者，其软骨肉瘤由右侧第一胸肋椎关节处骨软骨瘤恶变所致，肿瘤向神经孔延伸并压迫脊髓。
尽管肋骨孤立性骨软骨瘤恶变罕见，但必须始终考虑到这种可能性。
