Department of Ophthalmology, Hennepin Healthcare, Minneapolis, Minnesota, USA; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.
Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.
Surv Ophthalmol. 2019 Nov-Dec;64(6):770-779. doi: 10.1016/j.survophthal.2019.06.001. Epub 2019 Jun 20.
Typical optic neuritis is an idiopathic demyelinating condition that is often associated with multiple sclerosis. This has been well characterized and has an excellent prognosis. Atypical optic neuritis can result from an inflammatory, infectious, or autoimmune disorder. Differentiating the two types of optic neuritis is paramount and may be challenging early on in the clinical course. This review describes the recent literature describing the pathophysiology, clinical presentation, neuroimaging, and management of these disorders.
典型的视神经炎是一种特发性脱髓鞘疾病,常与多发性硬化症有关。这种疾病已经得到了很好的描述,并且预后良好。非典型视神经炎可由炎症、感染或自身免疫性疾病引起。区分这两种类型的视神经炎至关重要,在疾病的早期可能具有挑战性。这篇综述描述了最近描述这些疾病的病理生理学、临床表现、神经影像学和治疗的文献。