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食管疣状癌内镜下切除经验及文献复习

Experience with endoscopic resection of oesophageal verrucous carcinoma and literature review.

作者信息

Soota Kaartik, Tirumanisetty Pratyusha, Lee Ye Jin, Holm Adrian

机构信息

Gastroenterology, University of Iowa Foundation, Iowa City, Iowa, USA.

Internal Medicine, Unity Hospital, Greece, New York, USA.

出版信息

BMJ Case Rep. 2019 Jun 21;12(6):e229576. doi: 10.1136/bcr-2019-229576.

DOI:10.1136/bcr-2019-229576
PMID:31229974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6605909/
Abstract

A 65-year-old male patient with chronic dysphagia was found to have a 2 cm mass at gastro-oesophageal junction on endoscopy. Biopsy showed squamous hyperplasia without malignancy. Controlled radial expansion balloon dilatation and partial resection were performed but the symptoms recurred. He finally underwent endoscopic mucosa resection and histology showed well-differentiated verruciform squamous proliferation limited to the mucosa. Small amounts of tumour remnants were treated during subsequent follow-up endoscopies and the patient has been tumour free since then. Diagnosis of oesophageal verrucous carcinoma can be challenging and could be managed with endoscopic resection. In this report, we review the literature and present our experience with a patient with oesophageal verrucous carcinoma.

摘要

一名65岁男性慢性吞咽困难患者在内镜检查中发现胃食管交界处有一个2厘米的肿块。活检显示为鳞状上皮增生,无恶性病变。进行了可控径向扩张球囊扩张术和部分切除术,但症状复发。他最终接受了内镜黏膜切除术,组织学检查显示为高分化疣状鳞状增生,局限于黏膜层。在随后的随访内镜检查中对少量肿瘤残余进行了处理,此后患者一直无肿瘤。食管疣状癌的诊断可能具有挑战性,可通过内镜切除术进行治疗。在本报告中,我们回顾了文献并介绍了我们对一名食管疣状癌患者的治疗经验。

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1
Experience with endoscopic resection of oesophageal verrucous carcinoma and literature review.食管疣状癌内镜下切除经验及文献复习
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Verrucous carcinoma of the esophagus - a case report and literature review.食管疣状癌——一例报告及文献综述
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Esophageal verrucous carcinoma arising from hyperkeratotic plaques associated with human papilloma virus type 51.食管疣状癌源于人乳头瘤病毒 51 型相关的角化过度斑块。
Dis Esophagus. 2010 Jul;23(5):E17-20. doi: 10.1111/j.1442-2050.2010.01087.x. Epub 2010 Jul 8.
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Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.内镜下黏膜下剥离术治疗非典型小疣状癌:一例报告
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Long-term survival in a patient with verrucous carcinoma of the esophagus.一名食管疣状癌患者的长期生存情况。
Am J Gastroenterol. 1996 May;91(5):1031-3.
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Verrucous carcinoma of the esophagus eluding multiple sets of endoscopic biopsies and endoscopic ultrasound: a case report and review of the literature.食管疣状癌多次内镜活检及内镜超声均未检出:1例病例报告并文献复习
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J La State Med Soc. 2011 Sep-Oct;163(5):251-3.
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本文引用的文献

1
Verrucous Squamous Cell Cancer in the Esophagus: An Obscure Diagnosis.食管疣状鳞状细胞癌:一种难以明确的诊断
Case Rep Gastroenterol. 2016 Aug 31;10(2):466-471. doi: 10.1159/000448070. eCollection 2016 May-Aug.
2
Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.内镜下黏膜下剥离术治疗非典型小疣状癌:一例报告
J Med Case Rep. 2016 Mar 25;10:74. doi: 10.1186/s13256-016-0866-y.
3
Verrucous Oesophageal Carcinoma: Single Case Report and Case Series Including 15 Patients - Issues for Consideration of Therapeutic Strategies.疣状食管癌:单病例报告及包含15例患者的病例系列——治疗策略的考量要点
Viszeralmedizin. 2014 Oct;30(5):346-52. doi: 10.1159/000368270. Epub 2014 Oct 10.
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Verrucous carcinoma of the esophagus: A case report and literature review.食管疣状癌:一例报告及文献复习
World J Clin Cases. 2014 Jul 16;2(7):284-8. doi: 10.12998/wjcc.v2.i7.284.
5
Verrucous carcinoma of the esophagus: a potential diagnostic dilemma.食管疣状癌:一个潜在的诊断难题。
Case Rep Gastroenterol. 2013 Nov 28;7(3):498-502. doi: 10.1159/000357303. eCollection 2013 Sep.
6
A case of esophageal squamous cell carcinoma with positive HPV 11.一例人乳头瘤病毒11型阳性的食管鳞状细胞癌病例。
Gastroenterol Hepatol. 2013 May;36(5):311-5. doi: 10.1016/j.gastrohep.2012.09.003. Epub 2012 Nov 27.
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Endoscopic diagnosis and treatment of esophageal verrucous squamous cell cancer.食管疣状鳞状细胞癌的内镜诊断与治疗
Dis Esophagus. 2014 Jul;27(5):452-6. doi: 10.1111/j.1442-2050.2012.01434.x. Epub 2012 Oct 15.
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Verrucous carcinoma of the esophagus: a rare variant of squamous cell carcinoma for which a preoperative diagnosis can be a difficult one to make.食管疣状癌:一种罕见的鳞状细胞癌变体,术前诊断可能很难做出。
J La State Med Soc. 2011 Sep-Oct;163(5):251-3.
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Esophageal verrucous carcinoma arising from hyperkeratotic plaques associated with human papilloma virus type 51.食管疣状癌源于人乳头瘤病毒 51 型相关的角化过度斑块。
Dis Esophagus. 2010 Jul;23(5):E17-20. doi: 10.1111/j.1442-2050.2010.01087.x. Epub 2010 Jul 8.
10
Verrucous carcinoma of the esophagus: a complex diagnosis.食管疣状癌:一项复杂的诊断。
Endoscopy. 2010;42 Suppl 2:E137-8. doi: 10.1055/s-0029-1244051. Epub 2010 Apr 19.