Malik A B, Bidani J A, Rich H G, McCully K S
Department of Medicine, Brown University School of Medicine, Providence, Rhode Island, USA.
Am J Gastroenterol. 1996 May;91(5):1031-3.
A 66-yr-old white male with a long-standing history of gastroesophageal reflux and Barrett's esophagus developed squamous cell dysplasia proximal to the site of the metaplastic epithelium. Two months later, he presented with progressive dysphagia. Upper endoscopy revealed near obliteration of the lumen from a large friable mass in the distal esophagus. Repeat endoscopic biopsies revealed areas of focal dysplasia but were inconclusive for the presence of malignancy. At surgery, a large inflammatory fibrotic mass was resected that was confirmed histologically to be a verrucous squamous cell carcinoma. Twenty-two months after the resection, there is no evidence of tumor recurrence. The case and relevant literature is discussed.
一名66岁的白人男性，有长期胃食管反流和巴雷特食管病史，在化生上皮部位近端发生了鳞状细胞发育异常。两个月后，他出现进行性吞咽困难。上消化道内镜检查显示，远端食管有一个大的易碎肿块，几乎使管腔闭塞。再次内镜活检发现局灶性发育异常区域，但对于是否存在恶性肿瘤尚无定论。手术切除了一个大的炎性纤维化肿块，组织学证实为疣状鳞状细胞癌。切除术后22个月，没有肿瘤复发的迹象。本文对该病例及相关文献进行了讨论。
