嗜酸性肉芽肿性多血管炎继发角膜溶解
Corneal melt secondary to eosinophilic granulomatosis with polyangiitis.
作者信息
Fennelly Evelyn, Greenan Emily, Murphy Conor C
机构信息
Dublin Mid-Leinster Intern Network, Mater Misericordiae University Hospital, Dublin, Ireland.
Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.
出版信息
BMJ Case Rep. 2019 Jun 21;12(6):e229859. doi: 10.1136/bcr-2019-229859.
Abstract
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare antineutrophil cytoplasmic antibody-associated vasculitis that can affect any organ system. It is most often characterised by chronic airway inflammation along with prominent peripheral blood eosinophilia, although the disease can affect the cardiovascular, gastrointestinal, renal or central nervous systems. Ocular manifestations are uncommon and when they do occur, are varied in their clinical presentations. To the best of our knowledge, this is the first case of corneal melt secondary to EGPA to have been reported.
摘要
嗜酸性肉芽肿性多血管炎（EGPA）是一种罕见的抗中性粒细胞胞浆抗体相关性血管炎，可累及任何器官系统。该病最常见的特征是慢性气道炎症伴外周血嗜酸性粒细胞显著增多，不过也可累及心血管、胃肠道、肾脏或中枢神经系统。眼部表现并不常见，一旦出现，临床表现多样。据我们所知，这是首例报道的继发于EGPA的角膜溶解病例。
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