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在同时感染布氏锥虫和曼氏血吸虫的小鼠中,对血吸虫感染的同源免疫和粪便虫卵排泄的干扰

Interference with homologous immunity and faecal egg excretion in Schistosoma infections in mice concurrently infected with Trypanosoma brucei and Schistosoma mansoni.

作者信息

Fagbemi B O

机构信息

Department of Veterinary Microbiology and Parasitology, University of Ibadan.

出版信息

Folia Parasitol (Praha). 1987;34(4):317-22.

PMID:3123344
Abstract

The effects of the blood protozoan, Trypanosoma brucei, was assessed on the homologous immunity to Schistosoma mansoni infection and the distribution of S. mansoni eggs in the tissues and faeces of dually infected mice. The trypanosome infection reduced the homologous protection induced by a primary S. mansoni infection against a challenge infection and the faecal excretion of eggs during the primary schistosome infection. The findings are discussed in relation to the immunosuppressive action of Trypanosoma infection.

摘要

评估了血液原生动物布氏锥虫对曼氏血吸虫感染的同源免疫以及双重感染小鼠组织和粪便中曼氏血吸虫卵分布的影响。锥虫感染降低了曼氏血吸虫初次感染诱导的针对攻击感染的同源保护作用,以及初次血吸虫感染期间粪便中卵的排泄量。结合锥虫感染的免疫抑制作用对这些发现进行了讨论。

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