Damber J E, Bergh A, Widmark A
Department of Physiology, University of Umeå, Sweden.
Int J Androl. 1987 Dec;10(6):785-91. doi: 10.1111/j.1365-2605.1987.tb00382.x.
The effect of an LHRH-agonist on testicular vasomotion was studied in adult hypophysectomized rats. At 0.5 and 1 h after injection of 1 microgram LHRH-agonist, no effect on vasomotion was observed, but after 2 h the pulsatile blood flow pattern had changed to continuous flow in 50% of the rats. At 4 h after treatment with LHRH-agonist, vasomotion was not detected in the testis of any rat. In addition, at the latter time an increased number of polymorphonuclear leucocytes (PMNs) were observed in testicular microvessels, and some PMNs had migrated into the interstitial space. These findings are discussed in relation to the well-known stimulatory effect of LHRH-agonists on testicular interstitial fluid volume.
在成年垂体切除的大鼠中研究了促黄体生成激素释放激素（LHRH）激动剂对睾丸血管运动的影响。注射1微克LHRH激动剂后0.5小时和1小时，未观察到对血管运动的影响，但2小时后，50%的大鼠搏动性血流模式转变为持续性血流。用LHRH激动剂治疗4小时后，在任何大鼠的睾丸中均未检测到血管运动。此外，在后期，在睾丸微血管中观察到多形核白细胞（PMN）数量增加，并且一些PMN已迁移到间质空间。结合LHRH激动剂对睾丸间质液体积的众所周知的刺激作用对这些发现进行了讨论。
