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影响艾滋病毒/艾滋病感染者坚持治疗的促进因素和障碍:定性研究视角

Facilitators and Barriers Affecting Adherence Among People Living With HIV/AIDS: A Qualitative Perspective.

作者信息

Ahmed Syed Imran, Farooqui Maryam, Syed Sulaiman Syed Azhar, Hassali Mohamed Azmi, Lee Christopher K C

机构信息

School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.

School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM), Kuala Lumpur, Malaysia.

出版信息

J Patient Exp. 2019 Mar;6(1):33-40. doi: 10.1177/2374373518770805. Epub 2018 Apr 24.

Abstract

BACKGROUND

It is widely accepted that for HIV-positive persons on highly active antiretroviral treatment, high levels of adherence to treatment regimens are essential for promoting viral suppression and preventing drug resistance.

OBJECTIVES

This qualitative study examines factors affecting the adherence to HIV/AIDS treatment among patients with HIV/AIDS at a local hospital in Malaysia.

METHODS

The data from purposefully selected patients were collected by in-depth interviews using a pretested interview guide. Saturation was reached at the 13th interview. All interviews were audio-taped and transcribed verbatim for analysis using thematic content analysis.

RESULTS

Fear and stigma of perceived negative image of HIV diagnosis, lack of disease understating, poor support from the community, and perceived severity or the treatment side effects were among the reasons of nonadherence. Appropriate education and motivation from the doctors and reduction in pill burden were suggested to improve adherence.

CONCLUSION

Educational interventions, self-management, and peer and community supports were among the factors suggested to improve adherence. This necessitates uncovering efficient ways to boost doctor-patient communication and recognizing the role of support group for the social and psychological well-being of the patients.

摘要

背景

人们普遍认为,对于接受高效抗逆转录病毒治疗的艾滋病毒呈阳性者而言,高度依从治疗方案对于促进病毒抑制和预防耐药性至关重要。

目的

这项定性研究调查了马来西亚一家当地医院中影响艾滋病毒/艾滋病患者坚持接受艾滋病毒/艾滋病治疗的因素。

方法

通过使用预先测试的访谈指南进行深入访谈,收集了从有目的地挑选出的患者那里获得的数据。在第13次访谈时达到了饱和。所有访谈都进行了录音,并逐字转录以使用主题内容分析法进行分析。

结果

对艾滋病毒诊断负面形象的恐惧和污名化、对疾病了解不足、社区支持不力以及对治疗副作用的感知严重性是不依从的原因。建议医生进行适当的教育和激励,并减轻药丸负担以提高依从性。

结论

教育干预、自我管理以及同伴和社区支持是被认为可提高依从性的因素。这就需要找到有效的方法来加强医患沟通,并认识到支持小组对患者社会和心理健康的作用。

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