Azia Ivo N, Mukumbang Ferdinand C, van Wyk Brian
School of Public Health, University of the Western Cape, South Africa.
South Afr J HIV Med. 2016 Sep 30;17(1):476. doi: 10.4102/sajhivmed.v17i1.476. eCollection 2016.
South Africa currently runs the largest public antiretroviral treatment (ART) programme in the world, with over 80% of people living with HIV and/or AIDS on ART. However, in order to appreciate the benefits of using ART, patients are subject to uncompromising and long-term commitments of taking at least 95% of their treatment as prescribed. Evidence shows that this level of adherence is seldom achieved because of a multilevel and sometimes interwoven myriad of factors.
We described the challenges faced by patients on ART in Vredenburg with regard to ART adherence.
A descriptive qualitative research design was used. Eighteen non-adhering patients on ART in the Vredenburg regional hospital were purposefully selected. Using a semi-structured interview guide, we conducted in-depth interviews with the study participants in their mother tongue (Afrikaans). The interviews were audio-taped, transcribed verbatim and translated into English. The data were analysed manually using the thematic content analysis method.
Stigma, disclosure, unemployment, lack of transport, insufficient feeding, disability grants and alternative forms of therapy were identified as major barriers to adherence, whereas inadequate follow-ups and lack of patient confidentiality came under major criticisms from the patients.
Interventions to address poverty, stigma, discrimination and disclosure should be integrated with group-based ART adherence models in Vredenburg while further quantitative investigations should be carried out to quantify the extent to which these factors impede adherence in the community.
南非目前运营着世界上最大的公共抗逆转录病毒治疗(ART)项目,超过80%的艾滋病毒感染者和/或艾滋病患者接受抗逆转录病毒治疗。然而,为了体会使用抗逆转录病毒治疗的益处,患者需要坚定且长期地承诺至少按规定服用95%的治疗药物。有证据表明,由于存在多层次且有时相互交织的众多因素,这种依从水平很少能实现。
我们描述了弗雷登堡接受抗逆转录病毒治疗的患者在治疗依从性方面面临的挑战。
采用描述性定性研究设计。从弗雷登堡地区医院有目的地选取了18名未坚持抗逆转录病毒治疗的患者。使用半结构化访谈指南,我们用他们的母语(南非荷兰语)对研究参与者进行了深入访谈。访谈进行了录音,逐字转录并翻译成英语。使用主题内容分析法对数据进行人工分析。
耻辱感、信息披露、失业、交通不便、食物不足、残疾补助金和替代治疗形式被确定为坚持治疗的主要障碍,而随访不足和缺乏患者保密受到患者的主要批评。
在弗雷登堡,解决贫困、耻辱感、歧视和信息披露问题的干预措施应与基于群体的抗逆转录病毒治疗依从性模式相结合,同时应开展进一步的定量调查,以量化这些因素在多大程度上阻碍社区中的治疗依从性。