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Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodentibacter pneumotropicus (Pasteurella pneumotropica) strain.实验感染高毒力 Rodentibacter pneumotropicus(Pasteurella pneumotropica)菌株的 BALB/c 和 C57BL/6 野生型小鼠体液免疫反应和病理学的比较分析。
BMC Microbiol. 2018 May 30;18(1):45. doi: 10.1186/s12866-018-1186-8.
2
From the [Pasteurella] pneumotropica complex to Rodentibacter spp.: an update on [Pasteurella] pneumotropica.从巴斯德氏菌属气肿亚种复合体到鼠咬热罗氏菌属:巴斯德氏菌属气肿亚种的最新研究进展。
Vet Microbiol. 2018 Apr;217:121-134. doi: 10.1016/j.vetmic.2018.03.011. Epub 2018 Mar 12.
3
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Int J Syst Evol Microbiol. 2017 Jun;67(6):1793-1806. doi: 10.1099/ijsem.0.001866. Epub 2017 Jun 20.
4
Clonal outbreaks of [ Pasteurella] pneumotropica biovar Heyl in two mouse colonies.两个小鼠种群中嗜肺巴斯德氏菌海氏生物变种的克隆性暴发。
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The Mammalian Microbiome and Its Importance in Laboratory Animal Research.哺乳动物微生物群及其在实验动物研究中的重要性。
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Lab Anim. 2014 Jul;48(3):178-192. doi: 10.1177/0023677213516312. Epub 2014 Feb 4.
9
Development of a multiplex PCR assay based on the 16S-23S rRNA internal transcribed spacer for the detection and identification of rodent Pasteurellaceae.建立基于 16S-23S rRNA 内部转录间隔区的多重 PCR 检测方法,用于鼠源巴斯德氏菌科的检测和鉴定。
J Microbiol Methods. 2013 Nov;95(2):256-61. doi: 10.1016/j.mimet.2013.09.005. Epub 2013 Sep 18.
10
Analysis of 16S-23S rRNA internal transcribed spacer regions in Pasteurellaceae isolated from laboratory rodents.从实验用啮齿动物中分离的巴斯德氏菌科的 16S-23S rRNA 内部转录间隔区分析。
J Microbiol Methods. 2012 Sep;90(3):342-9. doi: 10.1016/j.mimet.2012.06.013. Epub 2012 Jul 4.

实验设施中鼠类物种的当前分布情况。

Current Distribution of Species Among the Mice and Rats of an Experimental Facility.

作者信息

Benga Laurentiu, Knorr Jeanette I, Engelhardt Eva, Gougoula Christina, Benten Peter M, Christensen Henrik, Sager Martin

机构信息

Central Unit for Animal Research and Animal Welfare Affairs, University Hospital, Heinrich-Heine University, Dusseldorf, Germany;, Email:

Central Unit for Animal Research and Animal Welfare Affairs, University Hospital, Heinrich-Heine University, Dusseldorf, Germany.

出版信息

J Am Assoc Lab Anim Sci. 2019 Jul 1;58(4):475-478. doi: 10.30802/AALAS-JAALAS-19-000001. Epub 2019 Jun 25.

DOI:10.30802/AALAS-JAALAS-19-000001
PMID:31239009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6643080/
Abstract

The uncertain taxonomy of [] and other rodent has hindered the acquisition of knowledge on the biology and disease for this group of bacteria. Recently, these organisms have been reclassified within the new genus In this study, we documented which of the new described spp. are present in the mouse and rat microbiologic units of an experimental facility. Screening all of the microbiologic units populated with mice and rats yielded 51 isolates. Molecular and phenotypic diagnosis indicated the colonization of mice by and , whereas and were found in rats. Overall, we document the association of laboratory rodents with 3 of the newly described . Diagnostics of the spp. at the species level can decisively contribute to the progress of knowledge on these bacteria.

摘要

[]及其他啮齿动物相关细菌不确定的分类法阻碍了对该类细菌生物学和疾病知识的获取。最近,这些微生物已被重新分类到新属中。在本研究中,我们记录了实验设施的小鼠和大鼠微生物单元中存在哪些新描述的[]物种。对所有有小鼠和大鼠的微生物单元进行筛选,共获得51株[]分离株。分子和表型诊断表明小鼠被[]和[]定植,而大鼠中发现了[]和[]。总体而言,我们记录了实验啮齿动物与3种新描述的[]物种的关联。在物种水平上对[]物种进行诊断可决定性地推动对这些细菌的认识进展。