Weiss J C, Melman S T
Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA.
Pediatr Infect Dis J. 1988 Jan;7(1):23-6. doi: 10.1097/00006454-198801000-00006.
If the initial use of amoxicillin fails to cure otitis media, a family will be burdened with medical costs for a second medication, additional office visit fees and time lost from employment. For some families the initial choice of a more expensive but more effective antibiotic may be more cost effective. Using a decision analysis approach we compared the cost effectiveness of amoxicillin and cefaclor. As the amoxicillin efficacy rate decreases or as parental salaries are increased, the cost-effective advantage moves towards cefaclor. With the decision analysis method described, a practitioner can use costs and efficacy rates relevant to his or her practice to determine the most cost-effective initial antibiotic for a child with otitis media.
如果最初使用阿莫西林未能治愈中耳炎，家庭将负担第二种药物的医疗费用、额外的门诊费用以及误工时间造成的损失。对于一些家庭来说，最初选择一种更昂贵但更有效的抗生素可能更具成本效益。我们采用决策分析方法比较了阿莫西林和头孢克洛的成本效益。随着阿莫西林有效率的降低或父母工资的增加，成本效益优势向头孢克洛转移。使用所描述的决策分析方法，从业者可以利用与其执业相关的成本和有效率来确定治疗中耳炎儿童最具成本效益的初始抗生素。
